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Merck
CN

855480

N-乙酰-5-羟色胺

99%

别名:

N-乙酰羟色胺, N-乙酰羟色胺

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经验公式(希尔记法):
C12H14N2O2
化学文摘社编号:
分子量:
218.25
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
214-916-5
MDL number:
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InChI key

MVAWJSIDNICKHF-UHFFFAOYSA-N

InChI

1S/C12H14N2O2/c1-8(15)13-5-4-9-7-14-12-3-2-10(16)6-11(9)12/h2-3,6-7,14,16H,4-5H2,1H3,(H,13,15)

SMILES string

CC(=O)NCCc1c[nH]c2ccc(O)cc12

assay

99%

mp

120-122 °C (lit.)

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

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Michał A Zmijewski et al.
Molecular and cellular endocrinology, 307(1-2), 211-216 (2009-05-05)
Since melatonin production has been documented in extrapineal and extraneuronal tissues, we investigated the expression of molecular elements of the melatoninergic system in human RPE cells (ARPE-19). The expression of key enzymes for melatonin synthesis: tryptophan hydroxylases (TPH1 and TPH2);
Gianluca Tosini et al.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 18(6), 645-653 (2012-05-16)
N-Acetylserotonin (NAS) is a naturally occurring chemical intermediate in biosynthesis of melatonin. Previous studies have shown that NAS has different brain distribution patterns from those of serotonin and melatonin, suggesting that NAS might have functions other than as a precursor
G F Oxenkrug et al.
Annals of the New York Academy of Sciences, 1122, 245-252 (2007-12-14)
The ability of methylene blue (MB) to inhibit the nitric oxide-induced stimulation of N-methyl-D-aspartate receptors has been suggested as a possible mechanism of MB's clinical antidepressant action. This study evaluated the alternative/additional mechanisms of the antidepressant effect of MB on
Jimo Borjigin et al.
Molecular and cellular endocrinology, 349(1), 13-19 (2011-07-26)
The pineal gland is a neuroendocrine organ of the brain. Its main task is to synthesize and secrete melatonin, a nocturnal hormone with diverse physiological functions. This review will focus on the central and pineal mechanisms in generation of mammalian
Eliângela Lima et al.
Epilepsy & behavior : E&B, 20(4), 607-612 (2011-04-02)
The goal of this study was to verify the effects of treatment with melatonin and N-acetylserotonin on the pilocarpine-induced epilepsy model. The animals were divided into four groups: (1) animals treated with saline (Saline); (2) animals that received pilocarpine and

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