assay
99%
optical activity
[α]22/D −35.9°, c = 2 in 6 M HCl
mp
280-285 °C (lit.)
SMILES string
C[C@H](N)C(=O)N[C@@H](C)C(O)=O
InChI
1S/C6H12N2O3/c1-3(7)5(9)8-4(2)6(10)11/h3-4H,7H2,1-2H3,(H,8,9)(H,10,11)/t3-,4-/m0/s1
InChI key
DEFJQIDDEAULHB-IMJSIDKUSA-N
法规信息
新产品
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Roland Wakiec et al.
Antimicrobial agents and chemotherapy, 52(11), 4057-4063 (2008-09-17)
The susceptibility to several oligopeptide and amino acid antifungals of a Saccharomyces cerevisiae strain carrying multiple deletions in yeast multidrug resistance genes was compared to transformants containing the CDR1, CDR2, or MDR1 genes that encode the major Candida albicans drug
Annegret Biegel et al.
Journal of medicinal chemistry, 48(13), 4410-4419 (2005-06-25)
The utilization of the membrane transport protein PEPT1 as a drug delivery system is a promising strategy to enhance the oral bioavailability of drugs. Since very little is known about the substrate binding site of PEPT1, computational methods are a
Alessandro Pedretti et al.
Bioorganic & medicinal chemistry, 19(15), 4544-4551 (2011-07-12)
Over the last years, considerable progress has been made for the identification and characterization of drug transporters, and several modeling studies have been undertaken to predict their effects on ADME profiling. Thus, this study was focused on the peptide transporter