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Merck
CN

861448

8-氮鸟嘌呤

98%

别名:

2-氨基-6-氧-8-氮杂嘌呤, 2-氨基-6-羟基-8-氮杂嘌呤, 癌散

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关于此项目

经验公式(希尔记法):
C4H4N6O
化学文摘社编号:
分子量:
152.11
EC Number:
205-148-1
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
171098
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InChI

1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)

InChI key

LPXQRXLUHJKZIE-UHFFFAOYSA-N

SMILES string

NC1=Nc2[nH]nnc2C(=O)N1

assay

98%

mp

>300 °C (lit.)

法规信息

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Bashir Mir et al.
Nucleic acids research, 32(3), e25-e25 (2004-02-13)
The use of primary somatic cells in nuclear transfer procedure has opened a new opportunity to manipulate domestic animal genomes via homologous recombination. To date, while a few loci have been targeted in somatic cells using similar enrichment strategies as
Yan-li Wei et al.
Guang pu xue yu guang pu fen xi = Guang pu, 24(7), 862-866 (2005-03-16)
The inclusion complexes of beta-Cyclodextrin (beta-CD) and HP-beta-Cyclodextrin (HP-beta-CD) with 6-Mercaptopurine (6-MP), Azathioprine (BAN) and 8-Azaguanine (Azan) were investigated by fluorescence. Various factors affecting the formation of inclusion complexes were discussed in detail including formation time and pH effect. The
A B Sarmento-Ribeiro et al.
Cancer investigation, 30(5), 331-342 (2012-02-22)
The involvement of apoptosis in the cytotoxicity mediated by nucleoside analogues, namely azaguanine, and its implication in resistance are not well understood. Using human T-cell acute lymphoblastic leukemia cell lines, sensitive (CEM cells) and resistant to azaguanine (CM3 cells), we
J H Park et al.
Hybridoma, 16(6), 551-556 (1998-02-10)
Macrophages are important constituents of the immune system by exerting phagocytosis on invading pathogens as well as secreting various immunoregulatory factors. Generation of human macrophage hybridoma has not been possible so far due to the lack of an appropriate fusion
Qiao-Ling Gong et al.
Journal of molecular modeling, 18(2), 493-500 (2011-05-05)
The interaction between 8-azaguanine (8-Azan) and bovine serum albumin (BSA) in Tris-HCl buffer solutions at pH 7.4 was investigated by means of fluorescence and ultraviolet-visible (UV-Vis) spectroscopy. At 298 K and 310 K, at a wavelength of excitation (λ (ex))

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