861448
8-氮鸟嘌呤
98%
别名:
2-氨基-6-氧-8-氮杂嘌呤, 2-氨基-6-羟基-8-氮杂嘌呤, 癌散
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关于此项目
经验公式（希尔记法）:
C4H4N6O
化学文摘社编号:
分子量:
152.11
EC Number:
205-148-1
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
171098
InChI
1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)
InChI key
LPXQRXLUHJKZIE-UHFFFAOYSA-N
SMILES string
NC1=Nc2[nH]nnc2C(=O)N1
assay
98%
mp
>300 °C (lit.)
法规信息
新产品
此项目有
Dong Chuan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59(13), 3131-3137 (2003-10-30)
A comparative study, luminescence behavior of 6-Mercaptopurine (6-MP), Azathiopurine (BAN), and 8-Azaguanine (8-Azan) have been investigated including the low temperature phosphorescence, the low temperature fluorescence, the room temperature phosphorescence (RTP) and the room temperature fluorescence (RTF). The effect of pH
Jacek Wierzchowski et al.
Nucleosides, nucleotides & nucleic acids, 24(5-7), 459-464 (2005-10-27)
Spectroscopic and kinetic studies of interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, an excellent fluorescent/fluorogenic substrate for the synthetic pathway of the reaction, and its 9-(2-phosphonylmethoxyethyl) derivative, a bisubstrate analogue inhibitor, were carried out. The goal was to
Yan-li Wei et al.
Guang pu xue yu guang pu fen xi = Guang pu, 24(7), 862-866 (2005-03-16)
The inclusion complexes of beta-Cyclodextrin (beta-CD) and HP-beta-Cyclodextrin (HP-beta-CD) with 6-Mercaptopurine (6-MP), Azathioprine (BAN) and 8-Azaguanine (Azan) were investigated by fluorescence. Various factors affecting the formation of inclusion complexes were discussed in detail including formation time and pH effect. The
A B Sarmento-Ribeiro et al.
Cancer investigation, 30(5), 331-342 (2012-02-22)
The involvement of apoptosis in the cytotoxicity mediated by nucleoside analogues, namely azaguanine, and its implication in resistance are not well understood. Using human T-cell acute lymphoblastic leukemia cell lines, sensitive (CEM cells) and resistant to azaguanine (CM3 cells), we
H Hata et al.
The Journal of veterinary medical science, 60(10), 1153-1155 (1998-11-20)
Nucleic acid biosynthesis of Angiostrongylus costaricensis was examined with various inhibitors; aminopterin (inhibitor of purine and pyrimidine de novo biosynthetic pathways), 8-azaguanine (specific inhibitor of purine salvage pathway) and PALA (specific inhibitor of pyrimidine de novo biosynthetic pathway) were applied
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