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Merck
CN

86728

1,4,7,10-四氮杂环十二烷-1,4,7,10-四基-四(甲基膦酸)

≥97.0% (CHN)

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经验公式(希尔记法):
C12H32N4O12P4
化学文摘社编号:
分子量:
548.30
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
3579556
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SMILES string

OP(O)(=O)CN1CCN(CCN(CCN(CC1)CP(O)(O)=O)CP(O)(O)=O)CP(O)(O)=O

assay

≥97.0% (CHN)

Other Notes

络合剂。镧系配合物用作 NMR 位移试剂;具有能与碱土金属络合的特性

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Ferenc K Kálmán et al.
Inorganic chemistry, 47(9), 3851-3862 (2008-04-03)
A cyclen-based ligand containing trans-acetate and trans-methylenephosphonate pendant groups, H 6DO2A2P, was synthesized and its protonation constants (12.6, 11.43, 5.95, 6.15, 2.88, and 2.77) were determined by pH-potentiometry and (1)H NMR spectroscopy. The first two protonations were shown to occur
A.D. Sherry et al.
Journal of Magnetic Resonance, 76, 528-528 (1988)
R. Delgado et al.
Helvetica Chimica Acta, 73, 140-140 (1990)
Anupama Datta et al.
Cancer biotherapy & radiopharmaceuticals, 24(1), 123-128 (2009-02-27)
The convenient synthetic methodology and in vivo stability of the bone-seeking gamma-radiation-emitting compound, (99m)Tc-DOTMP are described in this paper. The radiolabeling efficiency was found to be >97%, and the stability in serum indicated that (99m)Tc remained bound to the chelate
Naoto T Ueno et al.
Clinical breast cancer, 9(3), 173-177 (2009-08-08)
Bone-targeted radiation therapy is an attractive strategy for addressing bone disease with minimal systemic toxicity. This pilot study was designed to determine the safety and efficacy of (166)Holmium (Ho)-DOTMP for irradiating malignant cells and adjacent marrow in women with bone-only

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