Application
Regenerez®聚(癸二酸甘油酯)是一种可生物吸收的弹性体。通过将PGS固化至所需的交联水平,可将其物理性能从弹性调至热固性(美国专利号9.359,472)。 PGS固有的弹性性能可用于多种再生医学和组织工程应用。
Features and Benefits
- 可生物吸收。
- 由天然代谢物(甘油和癸二酸)组成。
- 可调的机械性能。
- 多功能平台,可进行进一步修改。
- 近似模拟人体组织的模量。
- 在无有害免疫反应的情况下促进愈合。
Legal Information
美国专利号9,359,472。
Regenerez is a registered trademark of The Secant Group, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
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No data available
flash_point_c
No data available
Samer H Zaky et al.
Biomedical materials (Bristol, England), 9(2), 025003-025003 (2014-02-04)
For bone engineering, the optimal scaffolding material and composition has yet to be elucidated. In this study, we investigated poly (glycerol sebacate) (PGS), an elastomer known primarily for its soft tissue regeneration ability, as a suitable substrate to support osteo-precursor
Synthesis, properties and biomedical applications of poly(glycerol sebacate) (PGS): A review.
Rai R, et al.
Progress in Polymer Science, 37 (8), 1051-1078 (2012)
Qi-Zhi Chen et al.
Journal of the mechanical behavior of biomedical materials, 4(8), 1805-1818 (2011-11-22)
Poly (glycerol sebacate) (PGS) is a promising elastomer for use in soft tissue engineering. However, it is difficult to achieve with PGS a satisfactory balance of mechanical compliance and degradation rate that meet the requirements of soft tissue engineering. In
Howard I Pryor et al.
Surgery, 146(3), 490-497 (2009-09-01)
The objectives of this study were to evaluate the efficacy of poly(glycerol) sebacate (PGS) films for the prevention of visceroparietal peritoneal (VP) adhesions and demonstrate the ease of laparoscopic PGS film placement. Peritoneal adhesions occur in nearly 95% of all
Wei Wu et al.
Nature medicine, 18(7), 1148-1153 (2012-06-26)
Host remodeling is important for the success of medical implants, including vascular substitutes. Synthetic and tissue-engineered grafts have yet to show clinical effectiveness in arteries smaller than 5 mm in diameter. We designed cell-free biodegradable elastomeric grafts that degrade rapidly
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