方案
≥95%
表单
powder or crystals
mp
98 °C
官能团
amine
phenyl
储存温度
−20°C
应用
N-Sulfinyltritylamine, TrNSO, is a stable linchpin reagent for the one-pot synthesis of diverse sulfonimidamides. Reported by the laboratory of Michael Willis, TrNSO can be used to join organometallic reagents and amines to assemble differentially substituted sulfonimidamides in high yields. TrNSO will find utility in medicinal and agrochemistry applications where more efficient synthetic methods are required for this increasingly significant functional group.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Thomas Q Davies et al.
Angewandte Chemie (International ed. in English), 56(47), 14937-14941 (2017-09-21)
Sulfonimidamides are increasingly important molecules in medicinal chemistry and agrochemistry, but their preparation requires lengthy synthetic sequences, which has likely limited their use. We describe a one-pot de novo synthesis of sulfonimidamides from widely available organometallic reagents and amines. This convenient
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