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Merck
CN

901553

Allyl-modified gelatin

gel strength 300 g Bloom, Degree of substitution: 70% by TNBS method

别名:

Gelatin-ene, Pentenoyl gelatin

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NACRES:
NA.23
UNSPSC Code:
12352202
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form

powder

color

white to pale yellow

suitability

conforms to structure for NMR

storage temp.

2-8°C

Application

Allyl-modified gelatin can be used in the synthesis of synthetic hydrogels, which can be potentially used in applications such as drug delivery and biosensors.
Gelatin has received significant attention in the biomedical field due to its inherent bioactivity. Functionalized gelatin can be crosslinked with the formation of covalent bonds into highly crosslinked structures, such as hydrogels. Recent literature suggests that radical-mediated polymerized hydrogels may not be ideal for cell and protein encapsulation due to radical-mediated damage, hindered molecular transport, or altered cell–cell/cell–material interactions. Allyl-modified gelatin can be used to form hydrogels with multifunctional thiol crosslinkers via thiol–ene click or Michael-addition reactions.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Monatshefte fur Chemie / Chemical Monthly null
Kedi Xu et al.
Acta biomaterialia, 9(11), 8802-8814 (2013-07-03)
Mesenchymal stromal/stem cells (MSCs) are considered promising cellular therapeutics in the fields of tissue engineering and regenerative medicine. MSCs secrete high concentrations of immunomodulatory cytokines and growth factors, which exert paracrine effects on infiltrating immune and resident cells in the
Gelatin hydrogels via thiol-ene chemistry
Russo L, et al.
Monatshefte fur Chemie / Chemical Monthly, 147(3), 587-592 (2016)
Gelatin hydrogels via thiol-ene chemistry.
Russo L, et al.
Monatshefte fur Chemie / Chemical Monthly, 147, 587-592 (2016)

商品

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.

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