产品名称
TissueFab® - GelMA-Vis, 0.2 μm sterile filtered, suitable for 3D bioprinting applications
description
Packaging size: 10ml
form
viscous liquid
impurities
<5 cfu/mL Bioburden
color
colorless to pale pink
pH
6.5-7.5
application(s)
3D bioprinting
storage temp.
2-8°C
Application
明胶甲基丙烯酰基（GelMA）是一种可聚合的水凝胶材料，衍生自天然细胞外基质（ECM）成分。由于其低成本，丰富性和天然细胞结合基序的保留，明胶已成为组织工程应用中高度寻求的材料。在GelMA中添加可光交联的甲基丙烯酰胺官能团可合成在生物学相关条件下稳定并促进细胞粘连，扩散和增殖的生物相容性，可生物降解和非免疫原性水凝胶。甲基丙烯酰胺官能团除快速胶凝作用外，还可用于控制水凝胶的孔径、降解率、溶胀比等物理参数。交联反应的时间和空间控制可以通过调节官能化程度和聚合条件来获得，从而允许制造具有独特图案，3D结构和形态的水凝胶。基于明胶甲基丙烯酸酯的生物墨水已用于生物打印成骨性、软骨性、肝性、成脂性、血管性、上皮性、内皮性、心脏瓣膜、皮肤、肿瘤和其他组织和构建体。
General description
3D生物打印是打印生物相容性材料，细胞，生长因子以及产生功能复杂的活组织所必需的其他支撑材料。3D生物打印已被用于生成几种不同类型的组织，例如皮肤，骨骼，血管移植物和软骨结构。基于所需的特性，可以使用不同的材料和配方来生成硬组织和软组织。尽管存在几种3D打印方法，但由于所用材料的敏感性，最常用的是基于生物墨水的基于挤压的方法。
Packaging
产品包含包装在玻璃瓶中的10 ml溶液。
Legal Information
TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1 - STOT RE 2
target_organs
Liver,Upper respiratory tract
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Gelatin-Based Hydrogels for Organ 3D Bioprinting.
Wang X, et al.
Polymers (Basel, Switzerland), 9, 401-401 (2017)
Jun Yin et al.
ACS applied materials & interfaces, 10(8), 6849-6857 (2018-02-07)
Methacrylated gelatin (GelMA) has been widely used as a tissue-engineered scaffold material, but only low-concentration GelMA hydrogels were found to be promising cell-laden bioinks with excellent cell viability. In this work, we reported a strategy for precise deposition of 5%
Christine McBeth et al.
Biofabrication, 9(1), 015009-015009 (2017-01-11)
Due to its relatively low level of antigenicity and high durability, titanium has successfully been used as the major material for biological implants. However, because the typical interface between titanium and tissue precludes adequate transmission of load into the surrounding
Y Shi et al.
Biomedical materials (Bristol, England), 13(3), 035008-035008 (2018-01-09)
Three-dimensional bioprinting is an emerging technology for fabricating living 3D constructs, and it has shown great promise in tissue engineering. Bioinks are scaffold materials mixed with cells used by 3D bioprinting to form a required cell-laden structure. In this paper
Wanjun Liu et al.
Advanced healthcare materials, 6(12) (2017-05-04)
Bioprinting is an emerging technique for the fabrication of 3D cell-laden constructs. However, the progress for generating a 3D complex physiological microenvironment has been hampered by a lack of advanced cell-responsive bioinks that enable bioprinting with high structural fidelity, particularly
商品
Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.
实验方案
Frequently asked questions (FAQs) for KAPA SYBR® FAST One-Step qRT-PCR Kits.
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