914169
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) dimethacrylate
average Mn ~12,500
别名:
PEG-PPG-PEG, Pluronic Dimethacrylate, Pluronic F-127 dimethacrylate, block-copolymers
产品名称
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) dimethacrylate, average Mn ~12,500
form
powder
mol wt
average Mn ~12,500
color
off-white to yellow
storage temp.
−20°C
Quality Level
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Application
Poloxamers are nonionic, triblock copolymers containg a central hydrophobic chain of poly(propylene glycol) (PPG) and two terminal hydrophilic chains of poly(ethylene glycol) (PEG). Due to their amphiphilic structure, poloxamer solutions feature temperature dependent self-assembling and thermo-gelling behavior. Concentrated aqueous solutions of poloxamers are liquid at low temperature and form a gel at higher temperature, in a reversible process. This characteristic has allowed for these materials to be used as drug carriers for most routes of administration including oral, topical, intranasal, ocular, and parenteral. Methacrylate-modified derivatives are most commonly used as thermosensitive hydrogels for drug delivery and 3D bioprinting applications. After casting or printing, the material can be crosslinked to preserve the hydrogel structure.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Self-Assembly of Pluronic F127 Diacrylate in Ethylammonium Nitrate: Structure, Rheology, and Ionic Conductivity before and after Photo-Cross-Linking.
Barron C R L, et al.
Macromolecules, 49(14), 5179-5189 (2016)
Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization.
Biase M D, et al.
Soft Materials, 7, 4928-4937 (2011)
J J Escobar-Chávez et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 9(3), 339-358 (2007-01-09)
It is, sometimes, desirable to maintain a constant plasma drug concentration within the therapeutically effective concentration range. The use of high viscosity hydromiscible vehicles such as hydrophilic gels, is one of various approaches for controlled drug delivery, and represents an
Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization.
Manuela D B, et al.
Soft Materials, 7, 4928-4937 (2011)
Christopher J Hansen et al.
Advanced materials (Deerfield Beach, Fla.), 25(1), 96-102 (2012-10-31)
Microvascular multinozzle arrays are designed and fabricated for high-throughput printing of functional materials. Ink-flow uniformity within these multigeneration, bifurcating microchannel arrays is characterized by computer modeling and microscopic particle image velocimetry (micro-PIV) measurements. Both single and dual multinozzle printheads are
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