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经验公式(希尔记法):
C19H18N2O5
化学文摘社编号:
分子量:
354.36
UNSPSC Code:
12352106
NACRES:
NA.22
MDL number:
InChI key
FBKUOPULLUJMOC-UHFFFAOYSA-N
SMILES string
O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NCC(=O)NCC(=O)O
InChI
1S/C19H18N2O5/c22-17(20-10-18(23)24)9-21-19(25)26-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,20,22)(H,21,25)(H,23,24)
assay
≥95%
form
powder or crystals
color
white to off-white
storage temp.
2-8°C
Quality Level
Application
Fmoc-Gly-Gly-OH is a lysosomally cleavable linker used in construction of antibody-drug conjugates (ADC & Bioconjugation).
Other Notes
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Alain Beck et al.
Nature reviews. Drug discovery, 16(5), 315-337 (2017-03-18)
Antibody-drug conjugates (ADCs) are one of the fastest growing classes of oncology therapeutics. After half a century of research, the approvals of brentuximab vedotin (in 2011) and trastuzumab emtansine (in 2013) have paved the way for ongoing clinical trials that
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