941514
Furan-2-carboxylic acid N-hydroxysuccinimide ester
别名:
(2,5-Dioxopyrrolidin-1-yl) furan-2-carboxylate, Furan-2-carboxylic acid NHS ester
方案
>90% (HPLC)
质量水平
表单
powder or crystals
环保替代产品得分
old score: 53
new score: 19
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环保替代产品特性
Safer Solvents and Auxiliaries
Design for Energy Efficiency
Inherently Safer Chemistry for Accident Prevention
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
颜色
white to off-white
溶解性
chloroform: 30 mg/mL
环保替代产品分类
储存温度
2-8°C
SMILES字符串
O=C(ON1C(=O)CCC1=O)C=2OC=CC2
一般描述
Furan-2-carboxylic acid N-hydroxysuccinimide ester is a versatile chemical compound belonging to the class of furan derivatives. Due to its ability to form stable amide bonds with primary amines, this compound is widely utilized in organic synthesis and bioconjugation techniques. Its unique furan ring structure imparts specific chemical properties that make it particularly valuable in medicinal chemistry and biochemistry for modifying biomolecules. The efficient nucleophilic substitution reactions it undergoes enable researchers to create stable amide bonds, making it an essential tool for peptide synthesis and biomolecule modification.
We are committed to bringing you Greener Alternative Products that adhere to one of the four categories of Greener Alternatives. This product belongs to the category of Re-engineered Products, demonstrating key improvements in Green Chemistry Principles such as "Safer Sovents and Auxiliaries", "Design for Energy Efficiency", and "Inherently Safer Chemistry for Accident Prevention." Click here to view its DOZN scorecard.
应用
Furan-2-carboxylic acid N-hydroxysuccinimide ester is ideal for a variety of scientific research applications, including:
- Organic Synthesis: Used in the synthesis of complex organic molecules and as a coupling agent in peptide synthesis.
- Biochemical Studies: Employed for the modification of proteins and peptides in various biochemical assays.
- Drug Development: Utilized in creating drug delivery systems and conjugating therapeutic agents to targeting molecules.
- Diagnostic and Therapeutic Production: Applied in producing bioconjugates for diagnostic and therapeutic purposes.
特点和优势
- Stable Amide Bond Formation: Reacts efficiently with primary amines to create robust amide bonds, crucial for bioconjugation.
- Efficient Reaction Mechanism: Forms a reactive ester intermediate that readily reacts with primary amines, ensuring high yields.
- Unique Furan Structure: Imparts specific chemical properties that enhance its utility compared to other N-hydroxysuccinimide esters.
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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