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Merck
CN

941514

Furan-2-carboxylic acid N-hydroxysuccinimide ester

greener alternative

别名:

(2,5-Dioxopyrrolidin-1-yl) furan-2-carboxylate, Furan-2-carboxylic acid NHS ester

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关于此项目

经验公式(希尔记法):
C9H7NO5
CAS Number:
分子量:
209.16
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.21
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方案

>90% (HPLC)

质量水平

表单

powder or crystals

环保替代产品得分

old score: 53
new score: 19
Find out more about DOZN™ Scoring

环保替代产品特性

Safer Solvents and Auxiliaries
Design for Energy Efficiency
Inherently Safer Chemistry for Accident Prevention
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

颜色

white to off-white

溶解性

chloroform: 30 mg/mL

环保替代产品分类

储存温度

2-8°C

SMILES字符串

O=C(ON1C(=O)CCC1=O)C=2OC=CC2

一般描述

Furan-2-carboxylic acid N-hydroxysuccinimide ester is a versatile chemical compound belonging to the class of furan derivatives. Due to its ability to form stable amide bonds with primary amines, this compound is widely utilized in organic synthesis and bioconjugation techniques. Its unique furan ring structure imparts specific chemical properties that make it particularly valuable in medicinal chemistry and biochemistry for modifying biomolecules. The efficient nucleophilic substitution reactions it undergoes enable researchers to create stable amide bonds, making it an essential tool for peptide synthesis and biomolecule modification.
We are committed to bringing you Greener Alternative Products that adhere to one of the four categories of Greener Alternatives. This product belongs to the category of Re-engineered Products, demonstrating key improvements in Green Chemistry Principles such as "Safer Sovents and Auxiliaries", "Design for Energy Efficiency", and "Inherently Safer Chemistry for Accident Prevention." Click here to view its DOZN scorecard.

应用

Furan-2-carboxylic acid N-hydroxysuccinimide ester is ideal for a variety of scientific research applications, including:
  • Organic Synthesis: Used in the synthesis of complex organic molecules and as a coupling agent in peptide synthesis.
  • Biochemical Studies: Employed for the modification of proteins and peptides in various biochemical assays.
  • Drug Development: Utilized in creating drug delivery systems and conjugating therapeutic agents to targeting molecules.
  • Diagnostic and Therapeutic Production: Applied in producing bioconjugates for diagnostic and therapeutic purposes.
Its ability to form stable amide bonds with primary amines makes Furan-2-carboxylic acid N-hydroxysuccinimide ester a highly valuable compound in advancing bioconjugation techniques and enhancing the functionality of biomolecules in research and development.

特点和优势

  • Stable Amide Bond Formation: Reacts efficiently with primary amines to create robust amide bonds, crucial for bioconjugation.
  • Efficient Reaction Mechanism: Forms a reactive ester intermediate that readily reacts with primary amines, ensuring high yields.
  • Unique Furan Structure: Imparts specific chemical properties that enhance its utility compared to other N-hydroxysuccinimide esters.

象形图

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警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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