Polycaprolactone dicarboxylic acid (PCL-diCOOH) is a linear difunctional polyester characterized by carboxylic acid groups at each terminal end. As part of the polycaprolactone family, PCL-diCOOH is a biodegradable and bioactive thermoplastic aliphatic polyester. Its unique structure and properties make it suitable for various applications, particularly in the biomedical field.

PCL-diCOOH is designed for a wide range of biomedical applications, leveraging its biodegradable and biocompatible nature. It is particularly effective in tissue engineering, regenerative medicine, and the development of medical devices. Its adaptability allows for innovative uses in 3D bioprinting of ostechondral tissues, as well as, in drug delivery systems, making it a versatile material for advancing healthcare solutions.

• Biocompatible: PCL is widely used in various biomedical applications and is recognized for its limited adverse biological responses.

• Biodegradable: As a member of the PCL family, PCL-diCOOH features controlled degradation properties that are particularly beneficial for tissue engineering and medical devices. While PCL generally degrades more slowly than other biodegradable polymers like PLGA and PLA, it can be blended with other biodegradable materials to achieve specific degradation rates tailored to customized solutions.

• Self-Healing/Smart Polymer Capabilities: The presence of carboxylic acid terminal groups in PCL-diCOOH enables potential self-healing properties through ionic interactions, enhancing the material′s durability and functionality.