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B103608

γ-丁内酯

Name: γ-丁内酯
Brand: ALDRICH

ReagentPlus^®, ≥99%

别名:

γ-羟基丁酸内酯, 4-羟基丁酸内酯, GBL

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关于此项目

经验公式（希尔记法）:

C₄H₆O₂

化学文摘社编号:

96-48-0

分子量:

86.09

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24891553

EC Number:

202-509-5

Beilstein/REAXYS Number:

105248

MDL number:

MFCD00005386

Assay:

≥99%

Form:

liquid

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属性

vapor density

3 (vs air)

Quality Level

200

vapor pressure

1.5 mmHg ( 20 °C)

product line

ReagentPlus^®

assay

≥99%

form

liquid

autoignition temp.

851 °F

expl. lim.

16 %

drug control

Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

refractive index

n20/D 1.436 (lit.)

bp

204-205 °C (lit.)

mp

−45 °C (lit.)

density

1.12 g/mL at 25 °C (lit.)

SMILES string

O=C1CCCO1

InChI

1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2

InChI key

YEJRWHAVMIAJKC-UHFFFAOYSA-N

说明

Application

用于引入3-羧丙基侧链。用作电池和电容器中电解质溶液的组成成分。

Biochem/physiol Actions

γ-羟基丁酸(GHB)前体。可通过阻断多巴胺能神经元的脉冲流，抑制多巴胺释放。 γ-丁内酯预处理可用于检测自身受体诱导的多巴胺释放。

γ-羟基丁酸(GHB)前体；抑制多巴胺释放。

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

GHS05,GHS07

signalword

Danger

hcodes

H302,H318,H336

pcodes

P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3

target_organs

Central nervous system

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

208.4 °F - closed cup

flash_point_c

98 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

易制毒化学品（3类）

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Journal of Power Sources, 43, 195-195 (1993)

Dual inhibitors of thromboxane A2 synthase and 5-lipoxygenase with scavenging activity of active oxygen species. Synthesis of a novel series of (3-pyridylmethyl)benzoquinone derivatives.

S Ohkawa et al.

Journal of medicinal chemistry, 34(1), 267-276 (1991-01-01)

A novel series of (3-pyridylmethyl)benzoquinone derivatives was molecular designed and synthesized for the dual purpose of inhibiting thromboxane A2 and leukotriene biosynthesis enzymes and scavenging active oxygen species (AOS). They were evaluated for inhibition of TXA2 synthase, inhibition of 5-lipoxygenase

The GIRK2 subunit is involved in IS-like seizures induced by GABA(B) receptor agonists.

Monica Blichowski et al.

Epilepsia, 56(7), 1081-1087 (2015-06-03)

Infantile spasms (or IS) is a catastrophic childhood epilepsy that is particularly prevalent in children with Down syndrome. Previously, we have shown that the Ts65Dn (Ts) mouse model of Down syndrome is a useful substrate upon which to develop an

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全球贸易项目编号

货号	GTIN
B103608-500G	04061837378041
B103608-25G	04061833420492
B103608-20KG	04061837378034
B103608-2.5KG	04061837378027