F5062
Fmoc-Lys(Me)3-OH Chloride
≥97%, for peptide synthesis
别名:
Fmoc-Lys(Me3Cl)-OH, N-alpha-Fmoc-N-alpha-trimethyl-N-L-lysine · chloride
产品名称
Fmoc-Lys(Me)3-OH Chloride, ≥97%
质量水平
方案
≥97%
表单
liquid
反应适用性
reaction type: Fmoc solid-phase peptide synthesis
应用
peptide synthesis
官能团
Fmoc
运输
dry ice
储存温度
−20°C
SMILES字符串
Cl.[N+](CCCC[C@H](N=C([O-])OCC1c2c(cccc2)c3c1cccc3)C(=O)O)(C)(C)C
InChI
1S/C24H30N2O4.ClH/c1-26(2,3)15-9-8-14-22(23(27)28)25-24(29)30-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21;/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H-,25,27,28,29);1H/t22-;/m0./s1
InChI key
XUJRNPVABVHOAJ-FTBISJDPSA-N
一般描述
Fmoc protected N-trimethyl lysine
应用
Fmoc-Lys(Me)3-OH chloride is one of the common N-terminal protected reagents used in the peptide synthesis. Some of the reported examples are:
- Synthesis of peptide linkers for monoclonal antibody-auristatin F conjugates.
- Preparation of multifunctional reagents with enhanced ionization properties for the analysis of protein modification in human cells and dynamic profiling of protein lipidation.
- Sequential peptide ligation to synthesize histone H3 containing a trimethyl lysine residue, with modified tail region.
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Sequential Peptide Ligation by Combining the Cys?Pro Ester (CPE) and Thioester Methods and Its Application to the Synthesis of Histone H3 Containing a Trimethyl Lysine Residue.
Kawakami T, et al.
Bulletin of the Chemical Society of Japan, 86(6), 690-697 (2013)
Multifunctional Reagents for Quantitative Proteome?Wide Analysis of Protein Modification in Human Cells and Dynamic Profiling of Protein Lipidation During Vertebrate Development.
Broncel M, et al.
Angewandte Chemie (International Edition in English), 54(20), 5948-5951 (2015)
Novel peptide linkers for highly potent antibody? auristatin conjugate.
Doronina S O, et al.
Bioconjugate Chemistry, 19(10), 1960-1963 (2008)
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