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Merck
CN

G10806

芦竹碱

97.5%

别名:

3-(二甲氨基甲基)吲哚, NSC 16892, 芦竹碱

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关于此项目

经验公式(希尔记法):
C11H14N2
化学文摘社编号:
分子量:
174.24
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-749-8
Beilstein/REAXYS Number:
140521
MDL number:
Assay:
97.5%
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Quality Level

assay

97.5%

mp

132-134 °C (lit.)

SMILES string

CN(C)Cc1c[nH]c2ccccc12

InChI

1S/C11H14N2/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11/h3-7,12H,8H2,1-2H3

InChI key

OCDGBSUVYYVKQZ-UHFFFAOYSA-N

Application

作为反应物用于制备:
  • 多巴胺D2受体拮抗剂
  • 抗疟疾药
  • 5-吲哚基-曼尼希碱
  • 增殖抑制剂
  • 人肥大细胞糜酶的抑制剂
  • DL-色氨酸的制备
  • 十字花科植物抗毒素黄铜素的潜在解毒抑制剂
  • 3-乙烯基吲哚
  • 血清素5-HT6受体配体模板
  • 选择性蛋白激酶cδ(PKCδ)下调因子


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pictograms

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signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

flash_point_f

332.6 °F

flash_point_c

167 °C

法规信息

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分析证书(COA)

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Sebastian Grün et al.
Phytochemistry, 66(11), 1264-1272 (2005-05-24)
Two indole alkaloids with defense related functions are synthesized in the genus Hordeum of the Triticeae. Gramine (3(dimethyl-amino-methyl)-indole) is found in H. spontaneum and in some varieties of H. vulgare, the benzoxazinoid 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one (DIBOA) is detected in H. roshevitzii, H.
Miho Chikazawa et al.
Journal of nutritional science and vitaminology, 64(1), 68-74 (2018-03-02)
Maintaining skeletal muscle functions by controlling muscle metabolism is of utmost importance. β2-Adrenergic receptor (β2-AR), which is expressed in skeletal muscle, is a member of the G-protein-coupled receptor family that plays a critical role in the maintenance of muscle mass.
Timothy Niacaris et al.
The Journal of experimental biology, 206(Pt 2), 223-231 (2002-12-13)
Caenorhabditis elegans feeds by rhythmically contracting its pharynx to ingest bacteria. The rate of pharyngeal contraction is increased by serotonin and suppressed by octopamine. Using an electrophysiological assay, we show that serotonin and octopamine regulate two additional aspects of pharyngeal



全球贸易项目编号

货号GTIN
G10806-25G04061833625026