N21200
2-硝基-1,4-苯二胺
95%
别名:
1,4-二氨基-2-硝基苯, 2-硝基对苯二胺
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关于此项目
线性分子式:
O2NC6H3(NH2)2
化学文摘社编号:
分子量:
153.14
Beilstein:
2210195
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
95%
表单
powder
mp
135-138 °C (lit.)
SMILES字符串
Nc1ccc(N)c(c1)[N+]([O-])=O
InChI
1S/C6H7N3O2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H,7-8H2
InChI key
HVHNMNGARPCGGD-UHFFFAOYSA-N
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Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
>372.2 °F - Pensky-Martens closed cup
闪点(°C)
> 189 °C - Pensky-Martens closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
1,4-Diamino-2-nitrobenzene (2-nitro-para-phenylenediamine).
IARC monographs on the evaluation of carcinogenic risks to humans, 57, 185-200 (1993-01-01)
Metabolism of the hair dye component, nitro-p-phenylenediamine, in the rat.
M Nakao et al.
Chemical & pharmaceutical bulletin, 35(2), 785-791 (1987-02-01)
S Bala et al.
Mutation research, 222(3), 141-148 (1989-03-01)
The antimutagenic effect of 10 citrus fruit juices was observed against the mutagenicity of N-nitro-o-phenylenediamine (NPD) in TA97a and sodium azide in TA100 tester strains of Salmonella typhimurium using the Ames test. It was noticed that the juices of all
Regioselective N-acetylation as a route of nitro-9-phenylenediamine metabolism by rat liver cytosol.
M Nakao et al.
Chemical & pharmaceutical bulletin, 38(9), 2561-2566 (1990-09-01)
Regioselectivity in N-acetylation of nitro-0-phenylenediamine, a widely used hair dye component, by rat liver cytosolic N-acetyltransferases was studied in relation to its substituent effects on enzymatic N-acetylation of mono-substituted anilines. Nitro-p-phenylenediamine was acetylated specifically at the N4-position to afford the
M Nakao et al.
Chemical & pharmaceutical bulletin, 39(1), 177-180 (1991-01-01)
Reductive metabolism of the hair dye constituent, nitro-p-phenylenediamine (2-nitro-1,4-diaminobenzene, NPDA), and its acetylated metabolite, NPDA N4-acetate, was investigated with rat liver subcellular fractions, microsomes and cytosol. Under anaerobic conditions, these compounds were reduced to their corresponding amines by these fractions.
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