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Merck
CN

P75202

L-焦谷氨酸

97%

别名:

(S)-(-)-2-吡咯烷酮-5-羧酸, (S)-5-氧-2-吡咯烷羧酸

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关于此项目

经验公式(希尔记法):
C5H7NO3
化学文摘社编号:
分子量:
129.11
EC Number:
202-700-3
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
82132
MDL number:
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assay

97%

form

crystalline powder

optical activity

[α]20/D −10°, c = 13 in H2O

color

white

mp

160-163 °C (lit.)

SMILES string

OC(=O)[C@@H]1CCC(=O)N1

InChI

1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1

InChI key

ODHCTXKNWHHXJC-VKHMYHEASA-N

Application

用于不对称合成和药物的结构单元。


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Journal of Heterocyclic Chemistry, 23, 1059-1059 (1986)
K L Yu et al.
Journal of medicinal chemistry, 31(7), 1430-1436 (1988-07-01)
Two series of conformationally constrained analogues of Pro-Leu-Gly-NH2 (PLG) have been synthesized. In one series of analogues, the Leu-Gly-NH2 dipeptide segment of PLG was replaced with the gamma-lactam residues 3(S)- and 3(R)-amino-2-oxopyrrolidineacetamide and the delta-lactam residue 3(S)-amino-2-oxopiperidineacetamide. The corresponding gamma-lactam
Russell W Friesen et al.
The Journal of nutrition, 137(12), 2641-2646 (2007-11-22)
Choline and glycine are inter-related through their roles in methyl metabolism. Choline is metabolized to betaine, which donates a methyl group to homocysteine to form methionine, also generating dimethylglycine, which is further metabolized to glycine. Choline is transported across the