assay
99%
optical activity
[α]20/D −31.5°, c = 1 in H2O
optical purity
ee: 99% (GLC)
mp
280-285 °C (dec.) (lit.)
SMILES string
N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
InChI
1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
InChI key
QIVBCDIJIAJPQS-VIFPVBQESA-N
Application
用于合成桥联吲哚生物碱。
Other Notes
血清素和褪黑素的氨基酸前体
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存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Journal of the Chemical Society. Chemical Communications, 1559-1559 (1994)
Claudia Temperini et al.
Bioorganic & medicinal chemistry, 16(18), 8373-8378 (2008-09-09)
An activation study of mammalian carbonic anhydrase (CA, EC 4.2.1.1) isoforms I-XIV with D- and L-tryptophan has been performed both by means of kinetic and X-ray crystallographic techniques. These compounds show a time dependent activity against isozyme CA II, with
Rafat M Mohareb et al.
Bioorganic & medicinal chemistry, 19(9), 2966-2974 (2011-04-16)
There is a great deal of interest in neurotrophin therapy to prevent neuronal degeneration. The present study aimed at synthesizing new functionalized indole derivatives with structures justifying neuroprotective activity using L-tryptophan (TRP) as starting material. The potential neuroprotective effect of