InChI key
ZOJBYZNEUISWFT-UHFFFAOYSA-N
SMILES string
C=CCN=C=S
InChI
1S/C4H5NS/c1-2-3-5-4-6/h2H,1,3H2
assay
97%
refractive index
n20/D 1.529 (lit.)
bp
150 °C (lit.)
mp
−80 °C (lit.)
density
1.013 g/mL at 25 °C (lit.)
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Biochem/physiol Actions
它是十字花科蔬菜的天然成分。
M Murata et al.
Free radical biology & medicine, 28(5), 797-805 (2000-04-08)
Several isothiocyanates have been proposed as promising chemopreventive agents for human cancers. However, it has been reported that allyl isothiocyanate exhibit carcinogenic potential, and benzyl isothiocyanate and phenethyl isothiocyanate have tumor-promoting activities. We investigated whether these isothiocyanates could cause DNA
Meng Zhao et al.
Molecular pain, 8, 55-55 (2012-07-31)
Oxaliplatin, a platinum-based chemotherapeutic agent, causes an unusual acute peripheral neuropathy. Oxaliplatin-induced acute peripheral neuropathy appears in almost all patients rapidly after infusion, and is triggered or exacerbated by cold, while its mechanisms are poorly understood. In this study, the
Jessica Marie Spradley et al.
Pain, 153(9), 1890-1897 (2012-07-10)
Many acute stressors reduce pain, a phenomenon called stress-induced antinociception (SIA). Stress also is associated with increased scratching in chronic itch conditions. We investigated effects of acute stressors on facial itch and pain using a recently introduced rat model. Under
De-Shou Cao et al.
PloS one, 7(5), e38005-e38005 (2012-06-16)
Several transient receptor potential (TRP) channels are expressed in pancreatic beta cells and have been proposed to be involved in insulin secretion. However, the endogenous ligands for these channels are far from clear. Here, we demonstrate the expression of the
Kazumasa Okubo et al.
British journal of pharmacology, 166(5), 1738-1743 (2012-02-04)
Hydrogen sulfide, a gasotransmitter, facilitates somatic pain signals via activation of Ca(v)3.2 T-type calcium channels in rats. Given evidence for the activation of transient receptor potential ankyrin-1 (TRPA1) channels by H(2)S, we asked whether TRPA1 channels, in addition to Ca(v)3.2
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