Merck
CN
所有图片(1)

文件

ALD00506

Sigma-Aldrich

Yu 硼化配体

≥95%

登录查看公司和协议定价
所有图片(1)
别名:
2,4-dimethoxyquinoline, Montanine
经验公式（希尔记法）:
C11H11NO2
CAS号:
40335-00-0
分子量:
189.21
MDL编号:
MFCD27950422
PubChem化学物质编号:
329772696
NACRES:
NA.22

检测方案

≥95%

形式

powder

反应适用性

reagent type: catalyst
reagent type: ligand
reaction type: C-H Activation

SMILES字符串

COC1=CC(OC)=NC2=CC=CC=C21

InChI

1S/C11H11NO2/c1-13-10-7-11(14-2)12-9-6-4-3-5-8(9)10/h3-7H,1-2H3

InChI key

XSZBLRGKCBUWRJ-UHFFFAOYSA-N

相关类别

一般描述

Yu Borylation Ligand, also referred to as 2,4-dimethoxyquinoline, has been developed by Professor Jin-Quan Yu and coworkers. 2,4-dimethoxyquinoline can be prepared by reacting 2,4-dichloroquinoline with sodium methoxide.

应用

The Yu Borylation Ligand in tandem with bis(pinacolato)diboron (Aldrich 473294) under palladium catalysis can promote direct borylation of C(sp3)-H bonds. Yu and coworkers have displayed this on both alanine-derived amides and cyclopropanes with directing group assistance from the Yu-Wasa Auxiliary (Aldrich 791806).
Yu Borylation Ligand (2,4-Dimethoxyquinoline) may be used as a starting reagent in the synthesis of 2,4 -dimethoxy-3-(3methylbut-2-enyl)quinoline and 4-methoxy-1H-quinolin-2-one. It may also be used in the preparation of isoprenyl derivatives.

其他说明

Ligand-Promoted Borylation of C(sp3)-H Bonds with Palladium(II) Catalysts

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°C)

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

为方便起见，与您过往购买产品相关的文件已保存在文档库中。

访问文档库

难以找到您所需的产品或批次号码？

在网站页面上，产品编号会附带包装尺寸/数量一起显示（例如：T1503-25G）。请确保 在“产品编号”字段中仅输入产品编号 (示例: T1503).

示例

T1503
货号
-
25G
包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

遇到问题？欢迎随时联系我们技术服务 寻求帮助

批号可以在产品标签上"批“ （Lot或Batch）字后面找到。

Aldrich 产品

  • 如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。

  • 如果您查询到的批号含有填充代码（例如05427ES-021），请输入去除填充代码-021的批号：05427ES。

  • 如果您查询到的批号含有填充代码（例如 STBB0728K9），请输入去除填充代码K9的批号：STBB0728。

未找到您寻找的产品？

部分情况下，可能未在线提供COA。如果搜索不到COA，可在线索取。

索取COA

Regioselective synthesis and biological evaluation of novel bis (2-chloroquinolines).
Rajesh K, et al.
Research on Chemical Intermediates, 39(9), 4259-4267 (2013)
Keith Jones et al.
Organic & biomolecular chemistry, 1(24), 4380-4383 (2003-12-20)
The synthesis of the quinoline alkaloid atanine 6, by selective demethylation of the 2,4-dimethoxyquinoline 11 is presented. An alternative demethylation utilising a thiolate anion leads to the regioisomeric 4-hydroxyquinoline 13.
Ultrasound-promoted synthesis of novel 2-chloroquinolin-4-pyrimidine carboxylate derivatives as potential antibacterial agents.
Balaji GL, et al.
Research on Chemical Intermediates, 39(4), 1807-1815 (2013)
Quinoline alkaloids. Part XIII. A convenient synthesis of furoquinoline alkaloids of the dictamnine type.
Collins JF, et al.
Journal of the Chemical Society. Perkin Transactions 1, 94-97 (1973)

相关内容

Yu Group – Professor Product Portal

The Yu program centers around the discovery of catalytic carbon–carbon and carbon–heteroatom bond forming reactions based on C–H activation. Target transformations are selected to enable 1) the use of simple and abundant starting materials such as aliphatic acids, amines and alcohols, and 2) disconnections that drastically shorten the synthesis of a drug molecule or a major class of biologically active compounds.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门