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Merck
CN

D124702

1,6-己二异氰酸酯

98%

别名:

六亚甲基二异氰酸酯

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线性分子式:
OCN(CH2)6NCO
化学文摘社编号:
分子量:
168.19
EC Number:
212-485-8
UNSPSC Code:
12162002
PubChem Substance ID:
Beilstein/REAXYS Number:
956709
MDL number:
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InChI key

RRAMGCGOFNQTLD-UHFFFAOYSA-N

InChI

1S/C8H12N2O2/c11-7-9-5-3-1-2-4-6-10-8-12/h1-6H2

SMILES string

O=C=NCCCCCCN=C=O

vapor pressure

0.05 mmHg ( 25 °C)

assay

98%

refractive index

n20/D 1.452 (lit.)

bp

255 °C (lit.)

density

1.04 g/mL at 25 °C (lit.)

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1C - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

flash_point_f

266.0 °F - Pensky-Martens closed cup

flash_point_c

130 °C - Pensky-Martens closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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历史批次信息供参考:

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G Bieler et al.
Occupational medicine (Oxford, England), 61(6), 440-442 (2011-08-10)
Occupational diisocyanate-induced extrinsic allergic alveolitis (EAA) is a rare and probably underestimated diagnosis. Two acute occupational EAA cases have been described in this context, but neither of them concerned hexamethylene diisocyanate (HDI) exposure. To investigate the cause of a life-threatening
M Janko et al.
American Industrial Hygiene Association journal, 53(5), 331-338 (1992-05-01)
Monitoring of exposure to 1,6-hexamethylene (HDI) monomers and HDI polyisocyanates in Oregon was initiated in 1980 and covered primarily spray painting and related activities. A total of 562 air samples were collected from 60 workplaces during the years 1980-1990 and
Sander M van Putten et al.
Journal of biomedical materials research. Part A, 98(4), 527-534 (2011-06-18)
Biomaterials are at continuous risk of bacterial contamination during production and application. In vivo, bacterial contamination of biomaterials delays the foreign body reaction (FBR). Endotoxins such as lipopolysaccharides (LPS), major constituents of the bacterial cell wall, are potent stimulators of
Zibiao Li et al.
Biomacromolecules, 13(12), 3977-3989 (2012-11-22)
This paper reports the synthesis and characterization of new hyperbranched amphiphilic polyurethane multiblock copolymers consisting of poly(propylene glycol) (PPG), poly(ethylene glycol) (PEG), and polycaprolactone (PCL) segments as in situ thermogels. The hyperbranched poly(PPG/PEG/PCL urethane)s, termed as HBPEC copolymers, were synthesized
Victoria Arrandale et al.
International archives of occupational and environmental health, 86(2), 167-175 (2012-03-14)
Despite the importance of skin exposure, studies of skin symptoms in relation to exposure and respiratory symptoms are rare. The goals of this study were to describe exposure-response relationships for skin symptoms, and to investigate associations between skin and respiratory

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