E152
Epiboxidine 盐酸盐
别名:
外-2-(3-甲基-5-异噁唑基)-7-氮杂双环[2.2.1]庚烷 盐酸盐
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关于此项目
经验公式（希尔记法）:
C10H14N2O · HCl
化学文摘社编号:
分子量:
214.69
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
InChI
1S/C10H14N2O.ClH/c1-6-4-10(13-12-6)8-5-7-2-3-9(8)11-7;/h4,7-9,11H,2-3,5H2,1H3;1H/t7-,8-,9+;/m0./s1
SMILES string
Cl.Cc1cc(on1)[C@H]2C[C@@H]3CC[C@H]2N3
InChI key
NSMIYECGCNTSSS-CTERPIQNSA-N
color
yellow
solubility
H2O: 22 mg/mL
storage temp.
−20°C
Biochem/physiol Actions
烟碱型乙酰胆碱受体的强效激动剂；地棘蛙素的类似物
Disclaimer
吸湿
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
B Badio et al.
European journal of pharmacology, 321(2), 189-194 (1997-02-26)
Synthetic (+/-)-epiboxidine (exo-2-(3-methyl-5-isoxazolyl)-7-azabicyclo[2.2.1]heptane) is a methylisoxazole analog of the alkaloid epibatidine, itself a potent nicotinic receptor agonist with antinociceptive activity. Epiboxidine contains a methylisoxazolyl ring replacing the chloropyridinyl ring of epibatidine. Thus, it is also an analog of another nicotinic
Manuel Tsiang et al.
Biochemistry, 50(10), 1567-1581 (2011-01-13)
We have developed a homogeneous time-resolved fluorescence resonance energy transfer (FRET)-based assay that detects the formation of HIV-1 integrase (IN) dimers. The assay utilizes IN monomers that express two different epitope tags that are recognized by their respective antibodies, coupled
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