H45132
5-羟基-Nω-甲基色胺草酸盐
99%
别名:
3-(2-甲基氨基乙基)吲哚-5-醇草酸盐, N-Methylserotonin oxalate
质量水平
方案
99%
mp
161-162 °C (dec.) (lit.)
SMILES字符串
OC(=O)C(O)=O.CNCCc1c[nH]c2ccc(O)cc12
InChI
1S/C11H14N2O.C2H2O4/c1-12-5-4-8-7-13-11-3-2-9(14)6-10(8)11;3-1(4)2(5)6/h2-3,6-7,12-14H,4-5H2,1H3;(H,3,4)(H,5,6)
InChI key
DYOZWAJOUTVNAF-UHFFFAOYSA-N
应用
- reactant for preparation of 5-HT receptor agonists
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Albrecht Pfäfflin et al.
Annals of clinical biochemistry, 46(Pt 2), 146-148 (2009-01-20)
Serotonin is frequently analysed by high-performance liquid chromatography (HPLC) with electrochemical detection. However, the accuracy of these methods may be affected by the presence of certain drugs. We describe for the first time the interference of paracetamol in therapeutic dosages
Sharla L Powell et al.
Journal of agricultural and food chemistry, 56(24), 11718-11726 (2008-12-04)
Cimicifuga racemosa (L.) Nutt. (syn. Actaea racemosa L., black cohosh) is used to relieve menopausal hot flashes, although clinical studies have provided conflicting data, and the active constituent(s) and mechanism(s) of action remain unknown. Because serotonergic receptors and transporters are
C R Ashby et al.
Synapse (New York, N.Y.), 17(3), 173-181 (1994-07-01)
In this study, we examined the interaction of 5-HT1A and 5-HT2A receptors in the rat medial prefrontal cortex (mPFc) using the techniques of extracellular single unit recording and microiontophoresis. The iontophoresis of the selective 5-HT1A receptor agonist (+-)-8-hydroxy-2-(di-n-propylamino) tetralin (8-OHDPAT)
P M Lalley et al.
The Journal of physiology, 487 ( Pt 3), 653-661 (1995-09-15)
1. The effects of the 5-HT2 receptor agonist alpha-methyl-5-HT were studied on the membrane of expiratory (E2) and post-inspiratory (PI) neurones, by intracellular recordings in the caudal medulla of anaesthetized cats. 2. Ionophoresis of alpha-Me-5-HT depolarized membrane potential and increased
A R Johnston et al.
Experimental brain research, 93(2), 293-298 (1993-01-01)
The effects of 5-hydroxytryptamine (5-HT) and related compounds on the discharge rate of tonically active medial vestibular nucleus (MVN) neurones were studied in an in vitro slice preparation of the dorsal brainstem of the rat. The majority (87 of 107
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