InChI
1S/C11H14N2O.C2H2O4/c1-12-5-4-8-7-13-11-3-2-9(14)6-10(8)11;3-1(4)2(5)6/h2-3,6-7,12-14H,4-5H2,1H3;(H,3,4)(H,5,6)
SMILES string
OC(=O)C(O)=O.CNCCc1c[nH]c2ccc(O)cc12
InChI key
DYOZWAJOUTVNAF-UHFFFAOYSA-N
assay
99%
mp
161-162 °C (dec.) (lit.)
Quality Level
Application
- reactant for preparation of 5-HT receptor agonists
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
D Alberghina et al.
Research in veterinary science, 90(3), 392-395 (2010-07-17)
To evaluate the changes in plasma and platelet serotonin (5-HT) as markers of the serotoninergic system in equines, 5-HT content was measured by high performance liquid chromatography (HPLC) in deproteinized plasma obtained from peripheral blood samples of 12 clinically healthy
A R Johnston et al.
Experimental brain research, 93(2), 293-298 (1993-01-01)
The effects of 5-hydroxytryptamine (5-HT) and related compounds on the discharge rate of tonically active medial vestibular nucleus (MVN) neurones were studied in an in vitro slice preparation of the dorsal brainstem of the rat. The majority (87 of 107
G L Laekeman et al.
Agents and actions, 16(5), 443-445 (1985-07-01)
Pharmacological effects of 5-hydroxykynuramine (5-HK) were investigated in chicken whole blood. It was shown that 5-HK had a time-depending inhibiting activity on platelet aggregation induced by 5-hydroxytryptamine (5-HT). Experiments were carried out in order to determine whether the inhibitory effect
Simultaneous micro-determination of serotonin and 5-hydroxyindole-3-acetic acid with 5-hydroxy-N omega-methyltryptamine, as an internal standard, in biological materials by high-performance liquid chromatography with electrochemical detection.
K Shibata et al.
Journal of chromatography, 430(2), 381-387 (1988-09-09)
Sharla L Powell et al.
Journal of agricultural and food chemistry, 56(24), 11718-11726 (2008-12-04)
Cimicifuga racemosa (L.) Nutt. (syn. Actaea racemosa L., black cohosh) is used to relieve menopausal hot flashes, although clinical studies have provided conflicting data, and the active constituent(s) and mechanism(s) of action remain unknown. Because serotonergic receptors and transporters are
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