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Merck
CN

I27902

异丙肾上腺素 盐酸盐

98%

别名:

(±)-异丙肾上腺素 盐酸盐, 1-(3′,4′-二羟基苯基)-2-异丙基氨基乙醇 盐酸盐, N-异丙基-DL-去甲肾上腺素 盐酸盐

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关于此项目

经验公式(希尔记法):
C11H17NO3 · HCl
化学文摘社编号:
分子量:
247.72
EC Number:
200-089-8
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
3917363
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InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI key

IROWCYIEJAOFOW-UHFFFAOYSA-N

SMILES string

Cl.CC(C)NCC(O)c1ccc(O)c(O)c1

assay

98%

mp

165-175 °C (dec.) (lit.)

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Biochem/physiol Actions

β-肾上腺素受体激活剂;增加胞质cAMP。

存储类别

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

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Jiao Li et al.
PloS one, 8(3), e58334-e58334 (2013-03-28)
Here we investigate how ß-adrenergic stimulation of the heart alters regulation of ryanodine receptors (RyRs) by intracellular Ca(2+) and Mg(2+) and the role of these changes in SR Ca(2+) release. RyRs were isolated from rat hearts, perfused in a Langendorff
M Morgan-Bathke et al.
Journal of dental research, 92(10), 911-917 (2013-07-26)
Autophagy is a catabolic pathway utilized to maintain a balance among the synthesis, degradation, and recycling of cellular components, thereby playing a role in cell growth, development, and homeostasis. Previous studies revealed that a conditional knockout of essential member(s) of
Aaron M Ring et al.
Nature, 502(7472), 575-579 (2013-09-24)
G-protein-coupled receptors (GPCRs) are integral membrane proteins that have an essential role in human physiology, yet the molecular processes through which they bind to their endogenous agonists and activate effector proteins remain poorly understood. So far, it has not been
Xin Pan et al.
Nature cell biology, 15(12), 1464-1472 (2013-11-12)
Mitochondrial calcium has been postulated to regulate a wide range of processes from bioenergetics to cell death. Here, we characterize a mouse model that lacks expression of the recently discovered mitochondrial calcium uniporter (MCU). Mitochondria derived from MCU(-/-) mice have
Sachin Nayyar et al.
American journal of physiology. Heart and circulatory physiology, 305(8), H1181-H1188 (2013-08-13)
QT variability (QTV) signifies repolarization lability, and increased QTV is a risk predictor for sudden cardiac death. The aim of the present study was to investigate the role of autonomic nervous system activity on QTV. This study was performed in

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