M14870
5-甲氧基芦竹碱
99%
别名:
5-甲氧基-3-二甲胺基甲基吲哚
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关于此项目
经验公式（希尔记法）:
C12H16N2O
化学文摘社编号:
分子量:
204.27
Beilstein:
170533
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
方案
99%
mp
123-126 °C (lit.)
SMILES字符串
COc1ccc2[nH]cc(CN(C)C)c2c1
InChI
1S/C12H16N2O/c1-14(2)8-9-7-13-12-5-4-10(15-3)6-11(9)12/h4-7,13H,8H2,1-3H3
InChI key
GOERTRUXQHDLHC-UHFFFAOYSA-N
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应用
- Reactant for preparation of dopamine D2 receptor antagonists
- Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction
- Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands
- Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents
- Reactant for preparation of indolylmethanesulfonamide and its methoxy derivatives
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
B M Clancy et al.
The Journal of pharmacology and experimental therapeutics, 242(1), 108-114 (1987-07-01)
The kinetics of agonist and antagonist interactions with the 5-hydroxytryptamine2 receptor were studied in the isolated rabbit aorta by following the antagonist-induced decrease in the steady-state response to an agonist. A model describing the competitive drug-receptor interactions was fitted to
Mark G Devlin et al.
European journal of pharmacology, 498(1-3), 59-69 (2004-09-15)
The effect of ligand pretreatment on human 5-hydroxytryptamine2C (5-HT2C) receptors was examined in CHO cells expressing high (CHO-1C7; 67+/-3 pmol/mg) or low (CHO-1C19; 72+/-10 fmol/mg) levels of the receptor. Seventy-two hours pretreatment of CHO-1C7 cells with various ligands did not
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