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Merck
CN

M2004

(S)-(+)-扁桃酸

ReagentPlus®, ≥99%

别名:

(S)-α-羟基苯乙酸

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线性分子式:
C6H5CH(OH)CO2H
化学文摘社编号:
分子量:
152.15
EC Number:
241-240-8
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
2208678
MDL number:
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InChI key

IWYDHOAUDWTVEP-ZETCQYMHSA-N

InChI

1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)/t7-/m0/s1

SMILES string

O[C@H](C(O)=O)c1ccccc1

product line

ReagentPlus®

assay

≥99%

optical activity

[α]20/D +154°, c = 2.8 in H2O

optical purity

ee: 99% (GLC)

mp

131-134 °C (lit.)

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General description

N-Methyl-D-glucamine (Meglumine) is a sorbitol derivative in which one of the hydroxyl groups has been replaced with a methylamino group. Meglumine is widely used with iodinated organic compounds as a contrast media.

Application

多功能试剂,用于拆分外消旋物和制备酰胺。
N-Methyl-D-glucamine can be used as a co-crystal conformer as well as a salt-forming agent due to its hydrophilic nature and ability to modify the crystalline structure of the drug molecule to improve solubility.
It is also used to functionalize polymers and resins to develop chelating agents for the removal of boron and arsenic from wastewater.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

>374.0 °F

flash_point_c

> 190 °C

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

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Tetrahedron, 50, 5049-5049 (1994)
The Journal of Organic Chemistry, 58, 2313-2313 (1993)
Synthetic Communications, 23, 2761-2761 (1993)
Melanie Balbach et al.
Frontiers in cell and developmental biology, 8, 572735-572735 (2020-09-29)
Mammalian oocytes are enveloped by the zona pellucida (ZP), an extracellular matrix of glycoproteins. In sperm, stimulation with ZP proteins evokes a rapid Ca2+ influx via the sperm-specific, pH-sensitive Ca2+ channel CatSper. However, the physiological role and molecular mechanisms underlying
A Lamouri et al.
Journal of medicinal chemistry, 36(8), 990-1000 (1993-04-16)
To further investigate our hypothesis on the structure of the platelet-activating factor (PAF) receptor, 35 compounds derived from 1,4-bis(3',4',5'-trimethoxybenzoyl)piperazine were synthesized and their in vitro antagonistic effect was measured. Substitution of the compounds in position 2, by ester or carbamate

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