M22601
1-(2-甲氧苯基)哌嗪
98%
别名:
1-（2-甲氧基苯基）哌嗪, 1-（o-甲氧基苯基）哌嗪, 1-（邻甲氧苯基）哌嗪, N-（2-甲氧基苯基）哌嗪, N-（邻甲氧基苯基）哌嗪, 邻甲氧基苯基哌嗪
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关于此项目
经验公式（希尔记法）:
C11H16N2O
化学文摘社编号:
分子量:
192.26
Beilstein:
167888
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
98%
折射率
n20/D 1.575 (lit.)
沸点
130-133 °C/0.1 mmHg (lit.)
mp
35-40 °C (lit.)
密度
1.095 g/mL at 25 °C (lit.)
SMILES字符串
COc1ccccc1N2CCNCC2
InChI
1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
InChI key
VNZLQLYBRIOLFZ-UHFFFAOYSA-N
基因信息
mouse ... Htr3a(15561)
rat ... Adra1a(29412), Drd2(24318), Htr1a(24473), Htr2a(29595), Htr7(65032)
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应用
1-(2-甲氧苯基)哌嗪可用于：
- 通过Aza-Michael加成反应官能化吡唑乙烯酮 (pyrazolylvinyl ketone) 类化合物。
- 制备环胺取代Tröger碱衍生物。
- 与[(1-甲基-2-巯基咪唑-5-基)羰基]琥珀酰亚胺反应，制备官能化双(巯基咪唑)硼酸酯。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
230.0 °F - closed cup
闪点(°C)
110 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Christian Mattsson et al.
International journal of hygiene and environmental health, 211(3-4), 458-462 (2007-09-18)
Occupational exposure to toluene diisocyanate (TDI) is a known occupational hazard and the occupational exposure limits in air are very low. One of the most common methods to monitor exposure to isocyanates is to sample air through filters impregnated with
Jan Boksa et al.
Polish journal of pharmacology, 55(6), 1013-1019 (2004-01-20)
A series of 15 new 2-H- and 2-substituted 5-[omega-[4-(2-methoxyphenyl)-piperazinyl]-alkyl]-1,2,3,4-tetrahydro-gamma-carboline derivatives were prepared, and their affinity for 5-HT1A and 5-HT2A serotonin receptors was determined. Most of those hybrid compounds were found to bind with high affinity to 5-HT1A sites (Ki <
Mehtap Tugrak et al.
Bioorganic chemistry, 90, 103095-103095 (2019-07-10)
New mono Mannich bases, (2-(4-hydroxy-3-((4-substituephenylpiperazin-1-yl)methyl)benzylidene)-2,3-dihydro-1H-inden-1-one), were prepared to evaluate their cytotoxic/anticancer properties and also their inhibitory effects on human carbonic anhydrase I and II isoenzymes (hCA I and II). Amine part was changed as [N-phenylpiperazine (1), N-benzylpiperazine (2), 1-(2-fluorophenyl)piperazine (3)
Hartmut Henneken et al.
Journal of environmental monitoring : JEM, 8(10), 1014-1019 (2007-01-24)
Diffusive sampling of methyl isocyanate (MIC) on 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole (NBDPZ)-coated glass fibre (GF) filters is strongly affected by high relative humidity (RH) conditions. It is shown that the humidity interference is a physical phenomenon, based on displacement of reagent from the
L Pawłowski
Polish journal of pharmacology and pharmacy, 35(4), 319-326 (1983-01-01)
1-(o-methoxyphenyl)-piperazine (o-MPP) is regarded as an antagonist of the dopamine receptor. Its effects were studied for the hind limb flexor reflex in the spinal rat, the body temperature in rats maintained at ambient temperature of 28 degrees C and stereotypy
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