方案
98%
mp
207-210 °C (dec.) (lit.)
SMILES字符串
NC(=O)C(O)=O
InChI
1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
InChI key
SOWBFZRMHSNYGE-UHFFFAOYSA-N
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储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Carlotta Granchi et al.
Journal of medicinal chemistry, 54(6), 1599-1612 (2011-02-22)
Highly invasive tumor cells are characterized by a metabolic switch, known as the Warburg effect, from "normal" oxidative phosphorylation to increased glycolysis even under sufficiently oxygenated conditions. This dependence on glycolysis also confers a growth advantage to cells present in
Seoung-ryoung Choi et al.
Journal of medicinal chemistry, 50(16), 3841-3850 (2007-07-20)
Plasmodium falciparum lactate dehydrogenase (pfLDH) is a key enzyme for energy generation of malarial parasites and is a potential antimalarial chemotherapeutic target. It is known that the oxamate moiety, a pyruvate analog, alone shows higher inhibition against pfLDH than human
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