P23989
N,N′-(1,4-亚苯基)二马来酰亚胺
97%
别名:
1,4-Dimaleimidobenzene, N,N′-(对亚苯基)二马来酰亚胺
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经验公式（希尔记法）:
C14H8N2O4
化学文摘社编号:
分子量:
268.22
EC Number:
221-910-6
UNSPSC Code:
12162002
PubChem Substance ID:
Beilstein/REAXYS Number:
249631
MDL number:
InChI key
AQGZJQNZNONGKY-UHFFFAOYSA-N
InChI
1S/C14H8N2O4/c17-11-5-6-12(18)15(11)9-1-2-10(4-3-9)16-13(19)7-8-14(16)20/h1-8H
SMILES string
O=C1C=CC(=O)N1c2ccc(cc2)N3C(=O)C=CC3=O
assay
97%
form
powder
mp
>300 °C (lit.)
M O Steinmetz et al.
The Journal of cell biology, 138(3), 559-574 (1997-08-11)
The effect of the type of metal ion (i.e., Ca2+, Mg2+, or none) bound to the high-affinity divalent cation binding site (HAS) of actin on filament assembly, structure, and dynamics was investigated in the absence and presence of the mushroom
Ryan N Mello et al.
Biophysical journal, 102(5), 1088-1096 (2012-03-13)
We have used thiol cross-linking and electron paramagnetic resonance (EPR) to resolve structural transitions of myosin's light chain domain (LCD) and catalytic domain (CD) that are associated with force generation. Spin labels were incorporated into the LCD of muscle fibers
K Polosukhina et al.
Biochemistry, 36(39), 11952-11958 (1997-10-08)
Rate constants for the reactions of Cys-697 and Cys-707 of skeletal muscle myosin subfragment 1 (S1) with N,N'-p-phenylenedimaleimide (pPDM) and its monofunctional analog phenylmaleimide (PM) were measured for S1 and S1 bound to nucleotides and/or actin. The [pPDM] and [PM]
L K Nitao et al.
Biochemistry, 37(47), 16704-16710 (1998-12-08)
Previous biochemical studies have shown that the SH1 (Cys707) and SH2 (Cys697) groups on rabbit skeletal myosin subfragment 1 (S1) can be cross-linked by using reagents of different cross-linking lengths. In the presence of nucleotide, this cross-linking is accelerated. In
Agnieszka Galińska-Rakoczy et al.
Journal of molecular biology, 387(4), 869-882 (2009-04-03)
The mechanism of salt-induced actin polymerization involves the energetically unfavorable nucleation step, followed by filament elongation by the addition of monomers. The use of a bifunctional cross-linker, N,N'-(1,4-phenylene)dimaleimide, revealed rapid formation of the so-called lower dimers (LD) in which actin
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