P38706
酞嗪
98%
别名:
β-苯并二氮杂卓, 2,3-二氮杂萘, 2,3-苯并二氮杂卓, 苯并[d]哒嗪
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关于此项目
经验公式（希尔记法）:
C8H6N2
化学文摘社编号:
分子量:
130.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
205-963-2
MDL number:
Assay:
98%
Form:
crystals
Quality Level
assay
98%
form
crystals
bp
189 °C/29 mmHg (lit.)
mp
89-92 °C (lit.)
storage temp.
2-8°C
SMILES string
c1ccc2cnncc2c1
InChI
1S/C8H6N2/c1-2-4-8-6-10-9-5-7(8)3-1/h1-6H
InChI key
LFSXCDWNBUNEEM-UHFFFAOYSA-N
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Muta. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Fadi M Awadallah et al.
European journal of medicinal chemistry, 52, 14-21 (2012-03-24)
New phthalazine-based vasodilators were synthesized through the chloroacylation of the starting compound 1-hydrazinophthalazine 4 to give the two key intermediates 5 and 7. These intermediates were used to alkylate various cyclic amines to furnish the final compounds 6a-h and 8a-h.
Michał Achmatowicz et al.
The Journal of organic chemistry, 74(2), 795-809 (2008-12-18)
p38 MAP kinase inhibitors have attracted considerable interest as potential agents for the treatment of inflammatory diseases. Herein, we describe a concise and efficient synthesis of inhibitor 1 that is based on a phthalazine scaffold. Highlights of our approach include
Manuel Sánchez-Moreno et al.
The Journal of antimicrobial chemotherapy, 67(2), 387-397 (2011-12-01)
To evaluate the in vitro leishmanicidal activity of imidazole-based (1-4) and pyrazole-based (5-6) benzo[g]phthalazine derivatives against Leishmania infantum and Leishmania braziliensis. The in vitro activity of compounds 1-6 was assayed on extracellular promastigote and axenic amastigote forms, and on intracellular
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P38706-1G | 04061834373179 |
| P38706-10G | 04061834373162 |