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Merck
CN

P39001

1-羟基酞嗪

99%

别名:

1-(2H)-酞嗪酮

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关于此项目

经验公式(希尔记法):
C8H6N2O
化学文摘社编号:
分子量:
146.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-319-8
Beilstein/REAXYS Number:
3654
MDL number:
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产品名称

1-羟基酞嗪, 99%

InChI

1S/C8H6N2O/c11-8-7-4-2-1-3-6(7)5-9-10-8/h1-5H,(H,10,11)

InChI key

IJAPPYDYQCXOEF-UHFFFAOYSA-N

SMILES string

O=C1NN=Cc2ccccc12

assay

99%

form

powder

mp

183-185 °C (lit.)

Quality Level

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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分析证书(COA)

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Craig Zetterberg et al.
Drug metabolism and disposition: the biological fate of chemicals, 44(8), 1286-1295 (2016-06-15)
(R)-2-((2-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)-2-methyl-N-(2,2,2-trifluoroethyl)butanamide (VX-509, decernotinib) is an oral Janus kinase 3 inhibitor that has been studied in patients with rheumatoid arthritis. Patients with rheumatoid arthritis often receive multiple medications, such as statins and steroids, to manage the signs and symptoms of comorbidities
Raghava Choudary Palacharla et al.
Xenobiotica; the fate of foreign compounds in biological systems, 49(2), 169-176 (2018-02-01)
The objective is to evaluate methoxsalen as an in vitro phenotyping tool in comparison to ABT as a nonspecific inactivator of P450 mediated metabolism. The reversible inhibition of methoxsalen and ABT against the P450, FMO, AO, MAO-A and -B, enzymes
Yasuhiro Uno et al.
Xenobiotica; the fate of foreign compounds in biological systems, 51(4), 494-499 (2021-01-13)
The cynomolgus macaque is a non-human primate species widely used in drug metabolism studies. Despite the importance of genetic polymorphisms in cytosolic aldehyde oxidase (AOX) 1 in humans, genetic variants have not been investigated in cynomolgus or rhesus macaques.Genetic variants
Takayuki Amano et al.
Biochemical pharmacology, 151, 69-78 (2018-03-10)
Dantrolene is used for malignant hyperthermia during anesthesia, and it sometimes causes severe liver injury as a side effect. Dantrolene is metabolized to acetylaminodantrolene, which is formed via the reduction of dantrolene to aminodantrolene and subsequent acetylation. Formation of hydroxylamine
Shengyun Huang et al.
Journal of separation science, 43(17), 3565-3572 (2020-07-07)
Capillary electrophoresis is a modern separation technique characterized by many benefits, which qualify it also for enzyme assays and the study of enzyme kinetics during drug development. Homogeneous or heterogeneous approaches can be followed for the enzymatic incubation. In this

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