T34908
D-甲状腺素
99%
别名:
3,3′,5,5′-四碘代-D-甲状腺原氨酸, 3-[4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基]-D-丙氨酸
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关于此项目
经验公式（希尔记法）:
C15H11I4NO4
化学文摘社编号:
分子量:
776.87
PubChem Substance ID:
UNSPSC Code:
12352101
Beilstein/REAXYS Number:
2954910
MDL number:
SMILES string
N[C@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O
InChI
1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m1/s1
InChI key
XUIIKFGFIJCVMT-GFCCVEGCSA-N
assay
99%
mp
~235 °C (dec.)
Gene Information
human ... THRA(7067), THRB(7068)
法规信息
新产品
此项目有
F Parker
Journal of the American Academy of Dermatology, 13(1), 1-30 (1985-07-01)
The ability to recognize diverse clinical forms of xanthomas, such as tuberous, planar, eruptive and tendinous, is important in the detection of underlying systemic disease. A variety of primary genetic disorders, as well as numerous secondary conditions such as diabetes
F Dorey et al.
Clinical endocrinology, 32(2), 221-228 (1990-02-01)
Selective pituitary resistance to thyroid hormone (PRTH) is responsible for thyrotoxicosis due to inappropriate secretion of TSH. The TSH suppressive action of D-thyroxine (DT4) has been previously documented in euthyroid and hypothyroid subjects. This prompted us to treat with DT4
Rational drug therapy of the hyperlipoproteinemias, Part II.
C B Blum et al.
Rational drug therapy, 20(10), 1-4 (1986-10-01)
R Narihara et al.
Neurochemistry international, 25(5), 451-454 (1994-11-01)
The effects of thyroxine and its related derivatives on gamma-aminobutyric acid (GABA) receptors in the rat brain were examined. D-Thyroxine strongly inhibited [3H]flunitrazepam binding to benzodiazepine receptor in crude synaptic membrane from the rat brain. The Scatchard analysis of the
R S Perry
Clinical pharmacy, 5(2), 113-127 (1986-02-01)
The biochemistry, etiology, and evaluation of hyperlipidemia and its management, including dietary and drug therapies, are discussed. Strong evidence supports the role of increased cholesterol concentrations as an independent risk factor for coronary artery disease (CAD); however, evidence that elevated
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