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线性分子式:
C6H5CH=C(C6H5)2
化学文摘社编号:
分子量:
256.34
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-395-1
Beilstein/REAXYS Number:
1867462
MDL number:
Assay:
99%
InChI
1S/C20H16/c1-4-10-17(11-5-1)16-20(18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-16H
InChI key
MKYQPGPNVYRMHI-UHFFFAOYSA-N
SMILES string
c1ccc(cc1)\C=C(/c2ccccc2)c3ccccc3
assay
99%
mp
69-71 °C (lit.)
Quality Level
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Application
三苯乙烯是一种芳香烃,可作为起始材料,通过以氟手性锰络合物为催化剂的不对称环氧化反应制备2,2,3-三苯基环氧乙烷。也可在MnO2和NaOAc存在下,与乙酸酐反应制备二氢-4,5,5-三苯基-2(3H)-呋喃酮。
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
E Bignon et al.
FEBS letters, 271(1-2), 54-58 (1990-10-01)
The activation of type I (gamma), II (beta) and III (alpha) protein kinase C (PKC) subspecies by phosphatidylserine (PS) and diacylglycerol (DAG) is inhibited by micromolar concentrations of triphenylacrylonitrile (TPE) antiestrogens. TPE A (with p-hydroxy and p-diethylaminoethoxy groups on the
Chellakkan S Blesson et al.
Steroids, 71(11-12), 993-1000 (2006-09-13)
The study was aimed to investigate the interaction of D,L-ormeloxifene (Orm), a triphenylethylene and its hydroxy derivative with estrogen receptor subtypes alpha and beta, its influence on ERE-driven transcriptional activation and progesterone receptor expression. In competitive binding experiments using human
Speculation on the mechanism of action of triphenylethylene antioestrogens.
C D van den Koedijk et al.
Biochemical pharmacology, 47(11), 1927-1937 (1994-06-01)
Yuliya Dobrydneva et al.
Journal of cardiovascular pharmacology, 50(4), 380-390 (2007-12-01)
The anti-estrogenic drug tamoxifen, which is used therapeutically for treatment and prevention of breast cancer, can lead to the development of thrombosis. We found that tamoxifen rapidly increased intracellular free calcium [Ca2+]i in human platelets from both male and female
H Wiseman et al.
Chemico-biological interactions, 79(2), 229-243 (1991-01-01)
The azole antifungal drug ketoconazole was found to inhibit Fe(III)-ascorbate dependent lipid peroxidation using either rat liver microsomes or ox-brain phospholipid liposomes as the substrate. It also inhibited microsomal peroxidation induced by the Fe(III)-ADP/NADPH system. The related azoles, miconazole and
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