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Merck
CN

W265608

麦芽酚

≥99.0%, FCC, FG

别名:

2-甲基-3-羟基-4-吡喃酮, 3-羟基-2-甲基-4 H -吡喃-4-酮, 落叶松酸, 麦芽醇

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关于此项目

经验公式(希尔记法):
C6H6O3
化学文摘社编号:
分子量:
126.11
FEMA Number:
2656
Council of Europe no.:
148
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
7.014
EC Number:
204-271-8
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
112169
Organoleptic:
caramel; jam; fruity; sweet
Grade:
FG
Fragrance grade
Halal
Kosher
Biological source:
synthetic
Agency:
follows IFRA guidelines
Food allergen:
no known allergens
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产品名称

麦芽酚, ≥99.0%, FCC, FG

SMILES string

CC1=C(O)C(=O)C=CO1

InChI key

XPCTZQVDEJYUGT-UHFFFAOYSA-N

InChI

1S/C6H6O3/c1-4-6(8)5(7)2-3-9-4/h2-3,8H,1H3

biological source

synthetic

grade

FG
Fragrance grade
Halal
Kosher

agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.515

assay

≥99.0%

autoignition temp.

1364 °F

expl. lim.

25 %

mp

160-164 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

organoleptic

caramel; jam; fruity; sweet

Quality Level

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Application


  • 马酚通过靶向PI3K/Akt/NF-κB通路预防骨关节炎的进展:体外和体内研究:本文详细介绍了马酚减轻骨关节炎的机制,重点关注其对关键信号通路的效用,这可能对治疗应用有益(Lu等人,2021年)。

  • 风味剂马酚对四氯化碳诱导的小鼠急性肝损伤的肝脏保护作用,通过抑制细胞凋亡和炎症反应:这项研究探讨了马酚的肝脏保护特性,证明了其在急性肝损伤模型中抑制细胞凋亡和炎症的潜力(Liu等人,2018年)。

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Xiao-Jie Mi et al.
Journal of agricultural and food chemistry, 67(5), 1392-1401 (2019-01-16)
Our previous study has confirmed that maltol can attenuate alcohol-induced acute hepatic damage and prevent oxidative stress in mice. Therefore, maltol might have the capacity to improve thioacetamide (TAA)-induced liver fibrosis. The purpose of this work was to explore the
Katherine H Thompson et al.
Chemical Society reviews, 35(6), 545-556 (2006-05-27)
The family of hydroxypyrones and close congeners, the hydroxypyridinones, is a particularly versatile class of ligands. The most widely investigated for medicinal applications are the 3-hydroxy-4-pyrones and the 1,2- 3,2- and 3,4-hydroxypyridinones. Key features of these ligands are: a six-membered
Huansong Wang et al.
Free radical research, 41(4), 479-488 (2007-04-25)
Soy sauce is a traditional fermented seasoning in Asian countries, that has high antioxidant activity in vitro and some antioxidant activity in vivo. We attempted to identify the major antioxidants present, using the 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay as a guide.
Wolfgang Kandioller et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(45), 12283-12291 (2009-10-13)
Organometallic ruthenium-arene compounds bearing a maltol ligand have been shown to be nearly inactive in in vitro anticancer assays, presumably due to the formation of dimeric Ru(II) species in aqueous solutions. In an attempt to stabilize such complexes, [Ru(eta(6)-p-cymene)(XY)Cl] (XY=pyrones
Stefano Amatori et al.
The Journal of organic chemistry, 77(5), 2207-2218 (2012-02-03)
The N,N'-bis[(3-hydroxy-4-pyron-2-yl)methyl]-N,N'-dimethylethylendiamine (malten) and 4,10-bis[(3-hydroxy-4-pyron-2-yl)methyl]-1,7-dimethyl-1,4,7,10-tetraazacyclododecane (maltonis) were synthesized and characterized. The acid-base behavior, structural characterizations, and biochemical studies in aqueous solution were reported. Each compound contains two 3-hydroxy-2-methyl-4-pyrone units (maltol) symmetrically spaced by a polyamine fragment, the 1,4-dimethylethylendiamine (malten), or

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