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Merck
CN

W525901

Sigma-Aldrich

香豆素,日本

别名:

香豆素, 1,2-苯并吡喃酮, 1-苯并吡喃-2-酮, 2H-苯并吡喃-2-酮

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关于此项目

经验公式(希尔记法):
C9H6O2
化学文摘社编号:
分子量:
146.14
Beilstein:
383644
EC 号:
MDL编号:
UNSPSC代码:
12164502
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生物来源

synthetic

蒸汽压

0.01 mmHg ( 47 °C)

来源

Japan origin

沸点

298 °C (lit.)

mp

68-73 °C (lit.)

SMILES字符串

O=C1Oc2ccccc2C=C1

InChI

1S/C9H6O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H

InChI key

ZYGHJZDHTFUPRJ-UHFFFAOYSA-N

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特点和优势

似新割干草。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

闪点(°F)

323.6 °F - closed cup

闪点(°C)

162 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Alfonso Maresca et al.
Bioorganic & medicinal chemistry letters, 20(24), 7255-7258 (2010-11-12)
Two series of disubstituted coumarins incorporating ether and acetyl/propionyl moieties in positions 6,7- and 7,8- of the heterocyclic ring were synthesized investigated for the inhibition of the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1). All these coumarins were very weak
Satoru Tamura et al.
Bioorganic & medicinal chemistry letters, 20(12), 3717-3720 (2010-05-25)
By use of the fission yeast expressing the model fusion protein comprised of GST, SV40 T antigen NLS, GFP, and Rev-NES in the bioassay, the prenylcoumarin osthol (1) was disclosed as the new Rev-export inhibitor from the MeOH extract of
Kazuto Takaishi et al.
Bioorganic & medicinal chemistry letters, 18(20), 5614-5617 (2008-09-17)
We synthesized all of the monomethoxycoumarins, 5-alkoxycoumarins and their derivatives, and investigated their nematicidal activity against the phytopathogenic nematode, Bursaphelenchus xylophilus. Among the compounds, 5-ethoxycoumarin showed the highest nematicidal activity. Furthermore, 5-ethoxycoumarin was comparatively harmless against both the brine shrimps
Alfonso Maresca et al.
Journal of medicinal chemistry, 53(1), 335-344 (2009-11-17)
Coumarin derivatives were recently shown to constitute a totally new class of inhibitors of the zinc metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1), being hydrolyzed within the CA active site to 2-hydroxycinnamic acids. We explore here a new series of variously
Björn C G Karlsson et al.
Journal of medicinal chemistry, 53(22), 7932-7937 (2010-10-27)
Here, we report the design, synthesis, and characterization of molecularly imprinted polymer (MIP) derived mimics of the human serum albumin (HSA) Sudlow I site-the binding site for the anticoagulant warfarin. MIP design was based upon a combination of experimental ((1)H

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