描述
Dox-NP™ (Liposomal Encapsulated Doxorubicin)
frozen liposomal suspension (buffer - 10% w/w sucrose, 10 mM histidine ~pH 6.5)
方案
>99% (HPLC/MS)
表单
dispersion
包装
pkg of 1 × 5 mL (300115S-1EA)
制造商/商品名称
Avanti Research™ - A Croda Brand
应用
advanced drug delivery
运输
dry ice
储存温度
−20°C
一般描述
Formulation: A Pegylated, long-circulating liposomal formulation with doxorubicin entrapped within an ammonium sulfate core via remote-loading. All unencapsulated was removed to yield a completely liposomal doxorubicin product. Liposomes are stored frozen for a longer shelf life.
应用
Dox-NP™(5mL vial) has been used as a sample to study its characteristics by asymmetrical-flow field flow fractionation (MD-AF4). It may also be used as an intravenous (i.v.) injection in flank or orthotopic animal models of cancer.
包装
10 mL amber serum vial (300115S-1EA)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Dox-NP is a trademark of Avanti Polar Lipids, LLC
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Physical characterization of liposomal drug formulations using multi-detector asymmetrical-flow field flow fractionation
Parot J, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society (2020)
J Parot et al.
Journal of controlled release : official journal of the Controlled Release Society, 320, 495-510 (2020-02-01)
Liposomal formulations for the treatment of cancer and other diseases are the most common form of nanotechnology enabled pharmaceuticals (NEPs) submitted for market approval and in clinical application today. The accurate characterization of their physical-chemical properties is a key requirement;
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