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经验公式（希尔记法）:
C27H44O2
化学文摘社编号:
分子量:
400.64
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
SMILES string
O1[C@H](C1(C)C)CC[C@H]([C@@H]2[C@@]3([C@H]([C@H]4[C@@H]([C@]5(CC[C@@H](CC5=CC4)O)C)CC3)CC2)C)C
InChI
1S/C27H44O2/c1-17(6-11-24-25(2,3)29-24)21-9-10-22-20-8-7-18-16-19(28)12-14-26(18,4)23(20)13-15-27(21,22)5/h7,17,19-24,28H,6,8-16H2,1-5H3/t17-,19+,20+,21-,22+,23+,24+,26+,27-/m1/s1
InChI key
OSENKJZWYQXHBN-XVYZBDJZSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700039P-1mg), pkg of 1 × 5 mg (700039P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
24(S),25-epoxycholesterol is an oxysterol, which is produced by fibroblasts, macrophages and brain cells.
24(S),25-epoxycholesterol is a cholesterol-derived oxysterol, which is produced by fibroblasts, macrophages, and the brain cells. 24(S),25-epoxycholesterol is synthesized de novo in the mevalonate pathway.
Application
24(S),25-epoxycholesterol has been used as an oxysterol/internalstandard to study the effects of AY9944-induced changes in neurospheres.
Biochem/physiol Actions
Exogenous addition of 24(S),25-epoxycholesterol lowers 3-hydroxy-3-methylglutaryl-Coenzyme A (HMG-CoA) reductase activity, represses sterol regulatory element-binding protein (SREBP) processing, and induces liver × receptor (LXR) -gene targets in vitro.
Packaging
5 mL Amber Glass Screw Cap Vial (700039P-1mg)
5 mL Amber Glass Screw Cap Vial (700039P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
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