产品名称
7-去氢胆甾醇, Avanti Research™ - A Croda Brand
description
Δ,5,7-cholesterol
packaging
pkg of 1 × 5 mg (700066P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
SMILES string
OC1CCC2(C3CCC4(C(CCC4C(CCCC(C)C)C)C3=CC=C2C1)C)C
InChI
1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3
InChI key
UCTLRSWJYQTBFZ-UHFFFAOYSA-N
assay
>99% (TLC)
form
powder
shipped in
dry ice
storage temp.
−70°C
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General description
7-脱氢胆固醇是胆固醇合成中产生的代谢物。它是一种主要存在于表皮中的不饱和甾醇。
Application
7-脱氢胆固醇已被用于：
- 在基于气相色谱/质谱（GC/MS）的甾醇分析中，定量少突胶质前体细胞（OPCs）中的7-脱氢胆固醇
- 作为内标物，用于使用超高效液相色谱-串联质谱（UHPLC-MS/MS）分析甾醇和羟固醇
- 作为内标物，用于通过液相(LC)-MS法测量脂质
Biochem/physiol Actions
7-脱氢胆固醇在高温和紫外线条件下作为维生素D3的前体。
Packaging
5 mL琥珀色玻璃螺旋盖样品瓶（700066P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Biosynthesis of Vitamin D in Skin
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Biomacromolecules, 6(5), 2455-2457 (2005-09-13)
These studies show that single-walled carbon nanotubes (SWNTs) can be effectively modified using phospholipids. Using a simple surface modification of SWNTs, followed by deposition of 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphoethanolamine (DCPE) phosphipid, results in stable water-dispersible SWNTs with highly uniform thickness.
Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP
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Cell Chemical Biology, 26(4), 593-599 (2019)
Metabolic Precursor of Cholesterol Causes Formation of Chained Aggregates of Liquid-Ordered Domains.
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Langmuir : the ACS journal of surfaces and colloids, 32(6), 1591-1600 (2016-01-20)
7-Dehydrocholesterol, an immediate metabolic predecessor of cholesterol, can accumulate in tissues due to some metabolic abnormalities, causing an array of symptoms known as Smith-Lemli-Opitz syndrome. Enrichment of cellular membranes with 7-dehydrocholesterol interferes with normal cell-signaling processes, which involve interaction between
Devanand K Shenoy et al.
Nano letters, 5(6), 1181-1185 (2005-06-10)
We demonstrate that polymerizable planar membranes permit reconstitution of protein ion channels formed by the bacterial toxins Staphylococcus aureus alpha-hemolysin (alphaHL) and Bacillus anthracis protective antigen 63. The alphaHL channel remained functional even after membrane polymerization. Surface pressure measurements suggest
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