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Merck
CN

700066P

Avanti

7-去氢胆甾醇

Avanti Research - A Croda Brand

别名:

7-脱氢胆固醇;维生素D3;110807

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关于此项目

经验公式(希尔记法):
C27H44O
化学文摘社编号:
分子量:
384.64
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25
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产品名称

7-去氢胆甾醇, Δ,5,7-cholesterol, powder

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 5 mg (700066P-5mg)

制造商/商品名称

Avanti Research - A Croda Brand 700066P

运输

dry ice

储存温度

−70°C

SMILES字符串

OC1CCC2(C3CCC4(C(CCC4C(CCCC(C)C)C)C3=CC=C2C1)C)C

InChI

1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3

InChI key

UCTLRSWJYQTBFZ-UHFFFAOYSA-N

一般描述

7-脱氢胆固醇是胆固醇合成中产生的代谢物。它是一种主要存在于表皮中的不饱和甾醇。

应用

7-脱氢胆固醇已被用于:
  • 在基于气相色谱/质谱(GC/MS)的甾醇分析中,定量少突胶质前体细胞(OPCs)中的7-脱氢胆固醇
  • 作为内标物,用于使用超高效液相色谱-串联质谱(UHPLC-MS/MS)分析甾醇和羟固醇
  • 作为内标物,用于通过液相(LC)-MS法测量脂质

生化/生理作用

7-脱氢胆固醇在高温和紫外线条件下作为维生素D3的前体。

包装

5 mL琥珀色玻璃螺旋盖样品瓶(700066P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Biosynthesis of Vitamin D in Skin
Principles of Medical Biology (1997)
Manish Sethi et al.
Nanoscale, 6(4), 2321-2327 (2014-01-15)
The effects of nanoparticle (NP) properties, such as size, shape and surface charge, on their efficacy and toxicity have been studied extensively. However, the effect of controlled drug release on NP efficacy and toxicity has not been thoroughly evaluated in
Galya Staneva et al.
Langmuir : the ACS journal of surfaces and colloids, 32(6), 1591-1600 (2016-01-20)
7-Dehydrocholesterol, an immediate metabolic predecessor of cholesterol, can accumulate in tissues due to some metabolic abnormalities, causing an array of symptoms known as Smith-Lemli-Opitz syndrome. Enrichment of cellular membranes with 7-dehydrocholesterol interferes with normal cell-signaling processes, which involve interaction between
Peng He et al.
Biomacromolecules, 6(5), 2455-2457 (2005-09-13)
These studies show that single-walled carbon nanotubes (SWNTs) can be effectively modified using phospholipids. Using a simple surface modification of SWNTs, followed by deposition of 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphoethanolamine (DCPE) phosphipid, results in stable water-dispersible SWNTs with highly uniform thickness.
Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP
Allimuthu D, et al.
Cell Chemical Biology, 26(4), 593-599 (2019)

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