描述
(25R)-cholest-4-en-26-oic acid, 3-oxo
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (700083P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
运输
dry ice
储存温度
−20°C
SMILES字符串
CC1(CC2)C(CCC3C1CCC4(C)C3CCC4C(CCCC(C)C(O)=O)C)=CC2=O
InChI key
PSXQJZDFWDKBIP-UHFFFAOYSA-N
一般描述
3-oxo-4-cholestenoic acid (3OChA) is synthesized from cholesterol by the oxidation at the positions C3 and C26 in the presence of P450 cytochromes (CYP125 and CYP142). This pathway is well established in M. smegmatis. 3OChA is an intermediate in cholesterol catabolism and is more soluble compared to cholesterol.
应用
3-oxo-4-cholestenoic acid has been used as a inducer ligand for the TetR-like repressor (KstR) of M. smegmatis.
生化/生理作用
3-oxo-4-cholestenoic acid (3OChA) acts as an inducer to the TetR-like repressor (KstR) and modulates the expression kstR regulon genes.
包装
5 mL Amber Glass Screw Cap Vial (700083P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
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