700131P
Avanti
24S,27-dihydroxycholesterol
Avanti Research™ - A Croda Brand
别名:
(25S)-cholest-5-en-3β,24S,27-triol
产品名称
24S,27-dihydroxycholesterol, Avanti Research™ - A Croda Brand 700131P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (700131P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 700131P
运输
dry ice
储存温度
−20°C
一般描述
24S,27-dihydroxycholesterol differs from 24S-hydroxycholesterol in steroid nucleus by having an additional hydroxyl group. 24S,27-dihydroxycholesterol is derived from 24S-hydroxycholesterol in the presence of enzyme cholesterol 24-hydroxylase (P450 46A1).
包装
5 mL Amber Glass Screw Cap Vial (700131P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Natalia Mast et al.
Biochemistry, 42(48), 14284-14292 (2003-12-03)
The known activity of cytochrome P450 46A1 (P450 46A1) is 24(S)-hydroxylation of cholesterol. This reaction produces biologically active oxysterol, 24(S)-hydroxycholesterol, and is also the first step in enzymatic degradation of cholesterol in the brain. We report here that P450 46A1
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