Product Name
7α,27-dihydroxycholesterol-d6, Avanti Research™ - A Croda Brand 700136P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (700136P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 700136P
运输
dry ice
储存温度
−20°C
一般描述
7α,27-dihydroxycholesterol (7α,27-di-OHC) is synthesized by the hydroxylation of 27-hydroxycholesterol (27-OHC). It is an oxysterol with side chains oxidized and is a structural isomer of 7α,25-dihydroxycholesterol. 7α,27-dihydroxycholesterol-d6 is a deuterated derivative of 7α,27-di-OHC.
应用
7α,27-dihydroxycholesterol-d6 has been used as a deuterated internal standard in liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS) for human plasma oxysterol analysis.
生化/生理作用
7α,27-dihydroxycholesterol (7α,27-di-OHC) is a ligand for Epstein-Barr virus-induced gene 2 (EBI2). 7α27-di-OHC is implicated in neurological disease, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome and diabetes by lipidomics analysis of human cerebrospinal fluid (CSF) samples. The levels of 7α,27-di-OHC decreases in lipopolysaccharide activation.
包装
5 mL Amber Glass Screw Cap Vial (700136P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
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