Merck
CN

700144P

Avanti

15:0 cholesteryl-d7 ester

Avanti Polar Lipids 700144P, powder

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别名:
cholesteryl-d7 pentadecanoate
经验公式(希尔记法):
C42H67D7O2
分子量:
618.08
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 10 mg (700144P-10mg)
pkg of 1 × 25 mg (700144P-25mg)

manufacturer/tradename

Avanti Polar Lipids 700144P

运输

dry ice

储存温度

−20°C

一般描述

15:0 cholesteryl-d7 ester (cholesteryl-d7 pentadecanoate) is a deuterated form of cholesteryl pentadecanoate ester. Cholesterol is found in free and ester form in circulation. It associates with lipoproteins including very-low, low and high-density lipoproteins (VLDL, LDL and HDL). The synthesis of cholesteryl esters is mediated by acylCoA-cholesteryl-acyl transferase (ACAT) majorly in the endoplasmic reticulum of liver and intestinal cells.

生化/生理作用

A ratio of cholesteryl ester to cholesterol is lower in cardiovascular disorder. The esterified cholesterol serves as the storage version of cholesterol and its association with lipoproteins further adds a structural feature to them.

包装

5 mL Amber Glass Screw Cap Vial (700144P-10mg)
5 mL Amber Glass Screw Cap Vial (700144P-25mg)

储存分类代码

11 - Combustible Solids

WGK

WGK 3


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Mathias J Gerl et al.
Scientific reports, 8(1), 14764-14764 (2018-10-05)
Shotgun lipidomic analysis of 203 lipids in 13 lipid classes performed on blood plasma of donors who had just suffered an acute coronary syndrome (ACS, n = 74), or an ischemic stroke (IS, n = 21), or who suffer from stable angina pectoris (SAP
Babak Bagheri et al.
Medical archives (Sarajevo, Bosnia and Herzegovina), 72(2), 103-107 (2018-05-08)
The hypothesis is proposed that the atherogenicity of lipoporotein fractions is correlated with the content of unesterified cholesterol. To evaluate the role and prognostic values of unesterified and esterified cholesterol in lipoprotein fractions for coronary artery disease (CAD). The study

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