InChI
1S/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-9,18-20,22-26,29H,10-17H2,1-6H3/b8-7+/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1
InChI key
OILXMJHPFNGGTO-ZAUYPBDWSA-N
SMILES string
CC1(CC[C@H](O)C2)C2=CCC3C1CCC4(C)C3CCC4C(/C=C/[C@H](C)C(C)C)C
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (700175P-5MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
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General description
Brassicasterol is a plant sterol, sharing similar structure with cholesterol. It is obtained through the dietary sources, including sea food.
Application
- Deciphering the effect of phytosterols on Alzheimer′s disease and Parkinson′s disease: the mediating role of lipid profiles: This research demonstrates the neuroprotective potential of phytosterols, including Brassicasterol, in modulating lipid profiles to mitigate symptoms of neurodegenerative diseases such as Alzheimer′s and Parkinson′s (Guo et al., 2024).
- Liposomal Phytosterols as LDL-Cholesterol-Lowering Agents in Diet-Induced Hyperlipidemia: Discusses the effectiveness of Brassicasterol and other phytosterols encapsulated in liposomes for reducing LDL cholesterol, showcasing a potential therapeutic approach in hyperlipidemia management (Poudel et al., 2023).
- Sterol Regulation of Development and 20-Hydroxyecdysone Biosynthetic and Signaling Genes in Drosophila melanogaster: Highlights the role of Brassicasterol in regulating developmental and hormonal pathways in model organisms, suggesting implications for developmental biology studies (Wen et al., 2023).
Biochem/physiol Actions
Brassica sterol in cerebrospinal fluid might serve as an indicator for Alzheimer′s disease. It is found in rapeseed oil. Brassicasterol is thus, useful in identifying brassica oil and contamination of rapeseed and canola oil in others. Plant sterols can penetrate through the blood brain barrier.
Packaging
5 mL Amber Glass Screw Cap Vial (700175P-5MG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Analysis of sterol compounds from Sambucus ebulus
Bubulica MV, et al.
Chemistry of Natural Compounds, 1-2 (2012)
The plant sterol brassicasterol as additional CSF biomarker in Alzheimer?s disease
Vanmierlo T, et al.
Acta Psychiatrica Scandinavica, 124(3), 184-192 (2011)
The search of new biomarkers to identify Alzheimer?s disease: An editorial comment to T. Vanmierlo et al.`The plant sterol brassicasterol and additional CFS biomarker in Alzheimer?s Disease?(1)
Lobo A and Quintanilla MA
Acta Psychiatrica Scandinavica, 124(3), 163-164 (2011)
Rapeseed and Canola Oil: Production, Processing, Properties and Uses, 60-60 (2004)
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