产品名称
Coag试剂II, Avanti Research™ - A Croda Brand 790413C
form
liquid
packaging
pkg of 1 × 2.5 mL (790413C-25mg), pkg of 2 × 4 mL (790413C-200mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 790413C
concentration
10 mg/mL (790413C-25mg), 25 mg/mL (790413C-200mg)
application(s)
microbiology
lipid type
phospholipids
shipped in
dry ice
storage temp.
−20°C
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General description
Coag Reagent II synthetic has the phospholipids 1,2-dioleoyl-sn-glycero-3-phosphocholine(DOPC) and 1,2-dioleoyl-sn-glycero-3-[phospho-l-serine] (DOPS) in the ratio 7:3w/w.
Application
Coag Reagent II may be used:
- in preparation of liposomes for liposome mechanical properties determination
- as a component of solubilization and crystallization buffer for the chemokine receptor CCR5, in large unilamellar vesicles (LUVs) preparation for cyclooxygenase (COX1 and COX-2) incorporation
- in equilibration of chip coated with anti-glutathione-S-transferase (GST) antibody for surface plasmon resonance (SPR) binding assay
Biochem/physiol Actions
1,2-dioleoyl-sn-glycero-3-phosphocholine(DOPC) and 1,2-dioleoyl-sn-glycero-3-[phospho-l-serine] (DOPS) mimics biological membranes of endosomes and exosomes and is useful in drug delivery.
Packaging
5 mL Clear Glass Sealed Ampule (790413C-200mg)
5 mL Clear Glass Sealed Ampule (790413C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Fast, efficient reconstitution of the cyclooxygenases into proteoliposomes
MirAfzali Z, et al.
Archives of Biochemistry and Biophysics, 443(1-2), 60-65 (2005)
A biosensor-based approach toward purification and crystallization of G protein-coupled receptors
Navratilova I, et al.
Analytical biochemistry, 353(2), 278-283 (2006)
Membrane lipid co-aggregation with alpha-synuclein fibrils
Hellstrand E, et al.
Testing, 8(10), 3260-3260 (2013)
Kathleen Allen Rodowicz et al.
Chemistry and physics of lipids, 163(8), 787-793 (2010-09-25)
Quantification of the mechanical properties of liposomes is critical in helping to predict their behavior during various applications such as targeted drug delivery, response to mechanical characterization or their interactions with isolated cytoskeletal elements. A numerical implementation of the Evans
Direct macromolecular drug delivery to cerebral ischemia area using neutrophil-mediated nanoparticles
Zhang C, et al.
Theranostics, 7(13), 3260-3260 (2017)
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