产品名称
bis(16:0 PE)-DTPA (Gd), Avanti Research™ - A Croda Brand 791298P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (791298P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 791298P
shipped in
dry ice
storage temp.
−20°C
General description
bis(16:0 PE)-DTPA (Gd) (bis(1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine)-N-N′-diethylenetriaminepentaacetic acid (gadolinium salt)) is a lipidic gadolinium complex, with four units of palmitic acid. The diethylenetriaminepentaacetic acid (DTPA) is chelated to gadolinium ion.
Biochem/physiol Actions
Gadolinium (Gd) has magnetic moment property and is potent magnetic resonance imaging (MRI) contrast agent. Diethylenetriaminepentaacetic acid attached to phosphatidylethanolamine (DTPA-PE) conjugated with Gd to form vesicles or liposomes improves the relaxivity of the Gd-DTPA complex while imaging. Targeted liposomes with Gd-DTPA (gadolinium-diethylenetriamine pentaacetic acid) facilitate tumor visualization and imaging.
Packaging
5 mL Amber Glass Screw Cap Vial (791298P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
新产品
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Yin Song et al.
Nanoscale research letters, 13(1), 380-380 (2018-11-30)
Enhanced MRI (magnetic resonance imaging) plays a vital role in the early detection of tumor but with low specificity. Molecular imaging of angiogenesis could efficiently deliver contrast agents to the tumor site by specific targeted carriers. We designed and synthesized
Tot Bui et al.
PloS one, 5(9) (2010-10-12)
Gadolinium (Gd), with its 7 unpaired electrons in 4f orbitals that provide a very large magnetic moment, is proven to be among the best agents for contrast enhanced MRI. Unfortunately, the most potent MR contrast agent based on Gd requires
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