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Merck
CN

791299P

Avanti

bis(18:0 PE)-DTPA (Gd)

Avanti Research - A Croda Brand

别名:

bis(1,2-distearoyl-sn-glycero-3-phosphoethanolamine)-N-N′-diethylenetriaminepentaacetic acid (gadolinium salt)

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关于此项目

经验公式(希尔记法):
C96H186GdN7O24P2
化学文摘社编号:
分子量:
2041.73
UNSPSC代码:
12352211
NACRES:
NA.25
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产品名称

bis(18:0 PE)-DTPA (Gd), Avanti Research - A Croda Brand 791299P, powder

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 5 mg (791299P-5mg)

制造商/商品名称

Avanti Research - A Croda Brand 791299P

运输

dry ice

储存温度

−20°C

一般描述

bis(1,2-distearoyl-sn-glycero-3-phosphoethanolamine)-N-N′-diethylenetriaminepentaacetic acid (gadolinium salt) or bis(18:0 PE)-DTPA (Gd) comprises four copies of stearic acid. It has DTPA in the head group of ethanolamine. The DTPA is attached to gadolinium ion.

生化/生理作用

Gadolinium salt based DTPA conjugated phospholipid is useful in magnetic resonance imaging (MRI) and multimodal imaging. Apart from being an MRI contrast agent, PE-DTPA (Gd) liposome is also flexible for modification for binding different targets using copper–free click–chemistry methodology.

包装

5 mL Amber Glass Screw Cap Vial (791299P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

法规信息

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分析证书(COA)

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Jin Young Kang et al.
Immunity, 31(6), 873-884 (2009-11-26)
Toll-like receptor 2 (TLR2) initiates potent immune responses by recognizing diacylated and triacylated lipopeptides. Its ligand specificity is controlled by whether it heterodimerizes with TLR1 or TLR6. We have determined the crystal structures of TLR2-TLR6-diacylated lipopeptide, TLR2-lipoteichoic acid, and TLR2-PE-DTPA
Pavlína Šimečková et al.
Scientific reports, 10(1), 4780-4780 (2020-03-18)
Gadolinium (Gd)-based contrast agents are extensively used for magnetic resonance imaging (MRI). Liposomes are potential nanocarrier-based biocompatible platforms for development of new generations of MRI diagnostics. Liposomes with Gd-complexes (Gd-lip) co-encapsulated with thrombolytic agents can serve both for imaging and

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