产品名称
bis(18:0 PE)-DTPA (Gd), Avanti Research™ - A Croda Brand 791299P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (791299P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 791299P
shipped in
dry ice
storage temp.
−20°C
General description
bis(1,2-distearoyl-sn-glycero-3-phosphoethanolamine)-N-N′-diethylenetriaminepentaacetic acid (gadolinium salt) or bis(18:0 PE)-DTPA (Gd) comprises four copies of stearic acid. It has DTPA in the head group of ethanolamine. The DTPA is attached to gadolinium ion.
Biochem/physiol Actions
Gadolinium salt based DTPA conjugated phospholipid is useful in magnetic resonance imaging (MRI) and multimodal imaging. Apart from being an MRI contrast agent, PE-DTPA (Gd) liposome is also flexible for modification for binding different targets using copper–free click–chemistry methodology.
Packaging
5 mL Amber Glass Screw Cap Vial (791299P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
新产品
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Jin Young Kang et al.
Immunity, 31(6), 873-884 (2009-11-26)
Toll-like receptor 2 (TLR2) initiates potent immune responses by recognizing diacylated and triacylated lipopeptides. Its ligand specificity is controlled by whether it heterodimerizes with TLR1 or TLR6. We have determined the crystal structures of TLR2-TLR6-diacylated lipopeptide, TLR2-lipoteichoic acid, and TLR2-PE-DTPA
Pavlína Šimečková et al.
Scientific reports, 10(1), 4780-4780 (2020-03-18)
Gadolinium (Gd)-based contrast agents are extensively used for magnetic resonance imaging (MRI). Liposomes are potential nanocarrier-based biocompatible platforms for development of new generations of MRI diagnostics. Liposomes with Gd-complexes (Gd-lip) co-encapsulated with thrombolytic agents can serve both for imaging and
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