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关于此项目
经验公式（希尔记法）:
C55H118N9O17P
化学文摘社编号:
分子量:
1208.55
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
18:0 PE-DTPA, Avanti Research™ - A Croda Brand 791300P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (791300P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 791300P
shipped in
dry ice
storage temp.
−20°C
General description
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (18:0 PE-DTPA) comprises synthetic phospholipid derivative of ethanolamine.
This chelate is used for preparing MRI contrast agents.
Application
18:0 PE-DTPA (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (ammonium salt)) has been used to chelate liposome-based cationic adjuvant formulation (CAF01). It has also been used in the liposome preparation for imaging studies
Biochem/physiol Actions
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (18:0 PE-DTPA) or PE-DTPA binding and interaction with the Toll-like receptor-2 regulates immune response . PE-DTPA acts as a lipopolysaccharide antagonist and elicits rescue functionality in sepsis by blocking nuclear factor κ -light-chain-enhancer of activated B cells based transcription.
Packaging
5 mL Amber Glass Screw Cap Vial (791300P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
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Pavlína Šimečková et al.
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