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关于此项目
经验公式（希尔记法）:
C45H71 D7O2
化学文摘社编号:
分子量:
658.14
MDL number:
NACRES:
NA.25
UNSPSC Code:
41141804
Assay:
>99% (TLC)
Form:
liquid
产品名称
18:1-d7-cholesterol, Avanti Research™ - A Croda Brand 791645C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (791645C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 791645C
concentration
1 mg/mL (791645C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
Cholesteryl oleate is a cholesteryl ester. 18:1-d7-cholesterol is a deuterated oleic acid cholesteryl ester.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
Application
18:1-d7-cholesterol may be used in the reconstitution of acetylated low-density lipoprotein (acLDL) liposome for trafficking studies in U2OS-SRA cells.
Biochem/physiol Actions
Elevation in cholesterol ester levels and its accumulation is implicated in prostate cancer (PCa). Cholesteryl oleate, may serve as a potential biomarker for diagnosis of PCa.
Packaging
5 mL Clear Glass Sealed Ampule (791645C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Heart Proteomics, 967-1009 (2001)
Jia Li et al.
Scientific reports, 6, 20984-20984 (2016-02-13)
In-depth delineation of lipid metabolism in prostate cancer (PCa) is significant to open new insights into prostate tumorigenesis and progression, and provide potential biomarkers with greater accuracy for improved diagnosis. Here, we performed lipidomics and transcriptomics in paired prostate cancer
McKenna Feltes et al.
Journal of lipid research, 60(3), 707-716 (2019-01-09)
Cholesterol is an essential structural component of cellular membranes and precursor molecule for oxysterol, bile acid, and hormone synthesis. The study of intracellular cholesterol trafficking pathways has been limited in part due to a lack of suitable cholesterol analogues. Herein
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