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Merck
CN

793024P

Avanti

DMG-PEG2000-Maleimide

Avanti Research - A Croda Brand

别名:

1,2-dimyristoyl-rac-glycero-3 -[maleimide (polyethylene glycol)-2000]

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关于此项目

经验公式(希尔记法):
C42H74N2O9
分子量:
751.04
UNSPSC Code:
12352211
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SMILES string

CCCCCCCCCCCCCC(=O)OCC(COCCOCCNC(=O)CCN1C(=O)C=CC1=O)OC(=O)CCCCCCCCCCCCC

biological source

synthetic

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (793024P-5MG)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

polymerizable lipids

shipped in

dry ice

storage temp.

−20°C

General description

DMG-PEG-2000-Maleimide, is a lipid excipient designed for the preparation of lipid nanoparticles (LNPs) for RNA delivery. It is derived from dimyristoyl glycerol (DMG) and exhibits similar properties as phospholipids in the way it associates with membranes.

Features and Benefits

The maleimide group reacts with thiol groups on peptides, enabling the conjugation of bioactive molecules to the surface of lipid nanoparticles. This distinctive property allows the design of LNPs specifically engineered for targeted delivery to particular cell types.

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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