跳转至内容
Merck
CN

810110C

Avanti

12-NBD Stearate

Avanti Research™ - A Croda Brand

别名:

12-N-methyl-(7-nitrobenz-2-oxa-1,3-diazo)aminostearic acid

登录查看公司和协议定价

选择尺寸

关于此项目

经验公式（希尔记法）:
C25H40N4O5
化学文摘社编号:
117056-67-4
分子量:
476.61
UNSPSC代码:
12352211
NACRES:
NA.25

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

12-NBD Stearate, Avanti Research™ - A Croda Brand 810110C

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 1 mL (810110C-1mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 810110C

浓度

1 mg/mL (810110C-1mg)

运输

dry ice

储存温度

−20°C

InChI

1S/C25H40N4O5/c1-3-4-5-12-15-20(16-13-10-8-6-7-9-11-14-17-23(30)31)28(2)21-18-19-22(29(32)33)25-24(21)26-34-27-25/h18-20H,3-17H2,1-2H3,(H,30,31)

InChI key

SAAVELCIPHKGJE-UHFFFAOYSA-N

一般描述

12-NBD Stearate is a fluorescent long-chain fatty acid (LCFA) derivative. It is amphipathic and a non-esterifiable fatty acid probe for incorporation into lipid droplets.

应用

12-NBD Stearate may be used:
  • as a ligand for fatty-acid binding protein 5 (FABP5) in competitive binding based high throughput fluorescence displacement assay
  • as a ligand for FABPs in spectrofluorometric measurements
  • as an inhibitor for FABP3, FABP5 and FABP7

生化/生理作用

12-NBD Stearate is unmetabolizable in HepG2 cells and colocalizes with α-caveolin-1 and its uptake is inhibited by filipin III. The sterol carrier protein-2 (SCP-2) 15-kDa isoform favors NBD Stearate transport compared to its 13.2-kDa isoform. The fatty-acid binding protein (FABP) expression in differentiating embryonic stem cells (ES) regulates the uptake of NBD Stearate. NBD Stearate is used majorly in fluorescence displacement binding assays of fatty-acid binding proteins.

包装

5 mL Amber Glass Screw Cap Vial (810110C-1mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia
Kaczocha M, et al.
PLoS ONE, 9(4) (2014)
Targeting fatty acid binding protein (FABP) anandamide transporters-a novel strategy for development of anti-inflammatory and anti-nociceptive drugs
Berger WT, et al.
PLoS ONE, 7(12) (2012)
Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia
Kaczocha M, et al.
Testing, 9(4) (2014)
Targeting fatty acid binding protein (FABP) anandamide transporters-a novel strategy for development of anti-inflammatory and anti-nociceptive drugs
Berger WT, et al.
Testing, 7(12) (2012)
Fatty acid-binding proteins transport N-acylethanolamines to nuclear receptors and are targets of endocannabinoid transport inhibitors
Kaczocha M, et al.
The Journal of Biological Chemistry, 287(5), 3415-3424 (2012)
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持